Category: Reagents

Reference: 9001181-5
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An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001181-50
€0.00 (tax incl.)
An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001369-1
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A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-10
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-25
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-5
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001373-25
€0.00 (tax incl.)
A tyramine metabolite; enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50s = 0.13 and 0.48 μg/ml for doxorubicin plus N-acetyltyramine and doxorubicin alone, respectively)
Reference: 9001373-5
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A tyramine metabolite; enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50s = 0.13 and 0.48 μg/ml for doxorubicin plus N-acetyltyramine and doxorubicin alone, respectively)
Reference: 9001475-10
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An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-100
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An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-25
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-50
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001479-5
€0.00 (tax incl.)
A quinone bacterial metabolite; inhibits the growth of a variety of bacteria (MICs = P. falciparum (IC80 = 0.0033 µM); inhibits proliferation of HCT116, A549, and HL-60 cancer cells (IC50s = 0.4, 4.1, and 0.8 µM,...
Reference: 9001510-1
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An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001510-10
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An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001510-5
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An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001533-1
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An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-10
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An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-25
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An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-5
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An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001535-1
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A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001535-10
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A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001535-5
€0.00 (tax incl.)
A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001536-1
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A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001536-10
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A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001536-5
€0.00 (tax incl.)
A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001577-1
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An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-10
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An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-25
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An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-5
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An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001589-1
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An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-10
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-25
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-5
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001737-1
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A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa
Reference: 9001737-10
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A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa
Reference: 9001737-25
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A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa
Reference: 9001737-5
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A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa
Reference: 9001799-1
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An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001799-10
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An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001799-25
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An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001799-5
€0.00 (tax incl.)
An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001800-1
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A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001800-5
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A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001800-500
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A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001820-10
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An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-100
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An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-5
€0.00 (tax incl.)
An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-50
€0.00 (tax incl.)
An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001827-50
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This small molecule library contains molecules that are known either to induce differentiation, to maintain self-renewal and proliferation, or to improve the reprogramming efficiency of various stem cell populations.
Reference: 9001839-1
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Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-10
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Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-25
€0.00 (tax incl.)
Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-5
€0.00 (tax incl.)
Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001845-10
€0.00 (tax incl.)
A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001845-25
€0.00 (tax incl.)
A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001845-5
€0.00 (tax incl.)
A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001873-100
€0.00 (tax incl.)
A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001873-25
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A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001873-50
€0.00 (tax incl.)
A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001879-1
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An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-10
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An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-5
€0.00 (tax incl.)
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-50
€0.00 (tax incl.)
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001881-10
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A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-25
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A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-5
€0.00 (tax incl.)
A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-50
€0.00 (tax incl.)
A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001893-10
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An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-25
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An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-5
€0.00 (tax incl.)
An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-50
€0.00 (tax incl.)
An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001902-1
€0.00 (tax incl.)
A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001902-5
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A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001902-500
€0.00 (tax incl.)
A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001920-1
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-10
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-25
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-5
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001925-500
€0.00 (tax incl.)
An antagonist of the vitamin D receptor; inhibits VDR-mediated target gene activation at 300 and 1,000 nM in reporter assays; decreases MacCM-induced secretion of IL-1β, IL-6, IL-8, CCL2, and RANTES in preadipocytes...
Reference: 9001935-1
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A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001935-10
€0.00 (tax incl.)
A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001935-5
€0.00 (tax incl.)
A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001937-100
€0.00 (tax incl.)
A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions
Reference: 9001937-25
€0.00 (tax incl.)
A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions
Reference: 9001937-50
€0.00 (tax incl.)
A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions

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