Dugesin C Reference: HY-N11663 Dugesin C is a diterpenoid isolated from the plant Salvia dugesii with a spiro carbocyclic ring system derived from the normal neocrotane skeleton.
PROTAC CDK9 ligand-1 Reference: HY-115729 PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
Decanedioic acid-d4 Reference: HY-W014787S Decanedioic acid-d4 is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].
Ponatinib Acid Reference: HY-135636 Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe.
N4-Benzoyl-2’-deoxy-5-iodocytidine Reference: HY-154660 N4-Benzoyl-2’-deoxy-5-iodocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
Thiolutin Reference: HY-N6712 Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation.
N3-PEG24-Hydrazide Reference: HY-133321 N3-PEG24-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Punicic acid Reference: HY-139066 Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and a ω-5 polyunsaturated fatty acid. Punicic acid has the potential for the research of various chronic diseases.
Bicalutamide Reference: HY-14249 Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer.
Methylisothiazolinone-d3 hydrochloride Reference: HY-W010243S Methylisothiazolinone-d3 (hydrochloride) is the deuterium labeled Methylisothiazolinone (hydrochloride). Methylisothiazolinone hydrochloride is the constituent of the biocide Kathon CG. Methylisothiazolinone hydrochloride is an isothiazolone derivative widely used as a preservative. Methylisothiazolinone hydrochloride is also a moderate sensitizer and reacts with GSH.
(E)-Methyl 4-coumarate Reference: HY-N2492 (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as Allium cepa or Morinda citrifolia L. leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.