Protein (306)

CD54 [ICAM-1] (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220ICAM1

€0.00 (tax incl.)

Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but...

CD278 [ICOS] (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220ICOS

€0.00 (tax incl.)

CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is...

Fc (human) IgG1 Control (rec.) (non-lytic)

Reference: CHI-HF-220IG1

€0.00 (tax incl.)

This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.

LTbetaR (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220LTBR

€0.00 (tax incl.)

The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B...

CD279 [PD-1] (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220PD1

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220PDL1

€0.00 (tax incl.)

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of...

CD273 [PD-L2] (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220PDL2

€0.00 (tax incl.)

T cells require a signal induced by the engagement of the T cell receptor and a “costimulatory” signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 [PD-L2] is one of...

SCF (human):Fc (human) (rec.) (non-lytic)

Reference: CHI-HF-220SCF

€0.00 (tax incl.)

Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival,...

IL-1alpha (human) (rec.) (His)

Reference: CHI-HR-20001A

€0.00 (tax incl.)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....

IL-1beta (human) (rec.) (His)

Reference: CHI-HR-20001B

€0.00 (tax incl.)

IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the...

IL-4 (human) (rec.) (His)

Reference: CHI-HR-20004

€0.00 (tax incl.)

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...

IL-8 (human) (rec.) (His)

Reference: CHI-HR-20008

€0.00 (tax incl.)

Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many...

IL-10 (human) (rec.) (His)

Reference: CHI-HR-20010

€0.00 (tax incl.)

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells...

IL-15 (human) (rec.) (His)

Reference: CHI-HR-20015

€0.00 (tax incl.)

Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems....

IL-18 (human) (rec.) (His)

Reference: CHI-HR-20018

€0.00 (tax incl.)

Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa...

IL-21 (mutant) (human) (rec.) (His)

Reference: CHI-HR-20021M

€0.00 (tax incl.)

Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B,...

BMP-2 (human) (rec.) (His)

Reference: CHI-HR-200BMP2

€0.00 (tax incl.)

Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation...

CCL5 (human) (rec.) (His)

Reference: CHI-HR-200CCL5

€0.00 (tax incl.)

CCL5, also known as RANTES (Regulated upon Activation Normal T cell Expressed and Secreted), is an 8kDa beta-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract...

CD134 [OX40] (human) (rec.) (His)

Reference: CHI-HR-200CD134

€0.00 (tax incl.)

CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen...

CD137 (human) (rec.) (His)

Reference: CHI-HR-200CD137

€0.00 (tax incl.)

Human CD137 (4-1BB) is a costimulatory molecule of the tumor necrosis factor (TNF) receptor superfamily. The glycoprotein 4-1BB is expressed mainly on activated CD4+ and CD8+ T cells and binds to a high-affinity...

CD27 (human) (rec.) (His)

Reference: CHI-HR-200CD27

€0.00 (tax incl.)

CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell...

HMGB1 (human) (rec.) (His)

Reference: CHI-HR-200HMGB1

€0.00 (tax incl.)

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as...

IFN-gamma (human) (rec.) (His)

Reference: CHI-HR-200IFNG

€0.00 (tax incl.)

IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune...

IL-2 (human) (rec.) (untagged)

Reference: CHI-HR-20602

€0.00 (tax incl.)

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...

IL-18 (human) (rec.)

Reference: CHI-HR-20618

€0.00 (tax incl.)

Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa...

IL-21 (human) (rec.) (untagged)

Reference: CHI-HR-20621

€0.00 (tax incl.)

Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B,...

FGF-21 (mouse) (rec.)

Reference: CHI-MF-102FGF21

€0.00 (tax incl.)

Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity....

IL-2 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-11002

€0.00 (tax incl.)

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...

IL-6R (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-11006R

€0.00 (tax incl.)

Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a...

IL-21 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-11021

€0.00 (tax incl.)

Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B,...

IL-22 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-11022

€0.00 (tax incl.)

Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1...

IL-33R (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-11033R

€0.00 (tax incl.)

Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T...

CD152 [CTLA-4] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110A4

€0.00 (tax incl.)

CD152 [CTLA-4] and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that...

CD275 [B7-H2] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110B7H2

€0.00 (tax incl.)

Mouse B7-H2, also called CD275, B7RP-1, B7h, LICOS and GL50, is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of...

CD276 [B7-H3] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110B7H3

€0.00 (tax incl.)

CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting cells and display...

B7-H4 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110B7H4

€0.00 (tax incl.)

B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation,...

BTNL2 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110BTNL2

€0.00 (tax incl.)

Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of which have been recently associated through genetic analysis; to sporadic inclusion body...

CCL20 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CCL20

€0.00 (tax incl.)

Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature...

CCL22 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CCL22

€0.00 (tax incl.)

CCL22 (C-C Motif Chemokine 22; Stimulated T cell chemotactic protein; STCP1) is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly...

CD28 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CD28

€0.00 (tax incl.)

CD28 and CTLA-4 together with their ligands, CD80 (B7-1) and CD86 (B7-2), constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous...

CD74 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CD74

€0.00 (tax incl.)

CD74 is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. The cytoplasmic portion of CD74 can be...

CD80 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CD80

€0.00 (tax incl.)

CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can bind to the...

CD83 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CD83

€0.00 (tax incl.)

Mouse CD83 is a 30-35kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells,...

CD86 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110CD86

€0.00 (tax incl.)

CD86 (B7-2) is a 60-100 kDa variably glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune...

GFRAL (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110GFRAL

€0.00 (tax incl.)

GFRAL (GDNF receptor alpha-like) is a distant member of the GDNFR family of proteins. Mouse GFR alpha-like contains a 330aa extracellular domain. It is expressed on hindbrain neurons of the CNS and functions as an...

CD278 [ICOS] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110ICOS

€0.00 (tax incl.)

CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is...

Fc (mouse) IgG2a Control (rec.)

Reference: CHI-MF-110IG2A

€0.00 (tax incl.)

This product should be used as the control protein for activity tests of fusion proteins including mouse target proteins and mouse IgG2a-Fc domains.

LYVE-1 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110LYVE1

€0.00 (tax incl.)

Lymphatic Vessel Endothelial Hyaluronan (HA) Receptor-1 (LYVE-1) is a 60-kDa type I transmembrane glycoprotein that is a member of the Link Protein superfamily. HA is found in the extracellular matrix of most animal...

CD279 [PD-1] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110PD1

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

CD274 [B7-H1/PD-L1] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110PDL1

€0.00 (tax incl.)

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of...

CD273 [PD-L2] (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110PDL2

€0.00 (tax incl.)

T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of...

SCF (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110SCF

€0.00 (tax incl.)

Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival,...

Tim-1 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110T1

€0.00 (tax incl.)

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections....

Tim-2 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110T2

€0.00 (tax incl.)

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.

Tim-3 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110T3

€0.00 (tax incl.)

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections....

Tim-4 (mouse):Fc (mouse) (rec.)

Reference: CHI-MF-110T4

€0.00 (tax incl.)

Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and...

IL-12 (mouse):Fc (human) (rec.)

Reference: CHI-MF-11112

€0.00 (tax incl.)

Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35...

IL-23 (mouse):Fc (human) (rec.)

Reference: CHI-MF-11123

€0.00 (tax incl.)

Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12 (1-5). Although p19 is expressed by...

IL-27 (mouse):Fc (human) (rec.)

Reference: CHI-MF-11127

€0.00 (tax incl.)

Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is...

IL-35 (mouse):Fc (human) (rec.)

Reference: CHI-MF-11135

€0.00 (tax incl.)

Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells (Treg) but not by resting or activated effector T cells (Teff). IL-35 is a heterodimeric protein composed of EBI3...

CD134 [OX40] (mouse):Fc (human) (rec.)

Reference: CHI-MF-111CD134

€0.00 (tax incl.)

CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen...

CD279 [PD-1] (mouse):Fc (human) (rec.)

Reference: CHI-MF-111PD1

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

Semaphorin-4A (mouse):Fc (human) (rec.)

Reference: CHI-MF-111SEMA4

€0.00 (tax incl.)

Semaphorin 4A (Sema4A, previously semB) is a Class 4 transmembrane Semaphorin with activity in the immune and nervous systems. Sema4A was first described as a molecule that enhances T cell activation and interacts...

Tim-1 (mouse):Fc (human) (rec.)

Reference: CHI-MF-111T1

€0.00 (tax incl.)

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections....

Tim-2 (mouse):Fc (human) (rec.)

Reference: CHI-MF-111T2

€0.00 (tax incl.)

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.

Tim-4 (mouse):Fc (human) (rec.)

Reference: CHI-MF-111T4

€0.00 (tax incl.)

Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and...

IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12002

€0.00 (tax incl.)

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...

IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12004

€0.00 (tax incl.)

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...

IL-6 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12006

€0.00 (tax incl.)

Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the...

IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12010

€0.00 (tax incl.)

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells...

IL-21 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12021

€0.00 (tax incl.)

Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B,...

IL-21R (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-12021R

€0.00 (tax incl.)

Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gammac) is required...

CD152 [CTLA-4] (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120A4

€0.00 (tax incl.)

CD152 [CTLA-4] and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that...

CD275 [B7-H2] (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120B7H2

€0.00 (tax incl.)

Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is...

CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120B7H3

€0.00 (tax incl.)

CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting cells and display...

CD200 (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120CD200

€0.00 (tax incl.)

CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted...

CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120ICAM1

€0.00 (tax incl.)

Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but...

Fc (mouse) IgG2a Control (rec.) (non-lytic)

Reference: CHI-MF-120IG2A

€0.00 (tax incl.)

This product should be used as the control protein for activity tests of fusion proteins including mouse target proteins and mouse IgG2a-Fc domains.

CD274 [B7-H1/PD-L1] (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120PDL1

€0.00 (tax incl.)

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of...

SCF (mouse):Fc (mouse) (rec.) (non-lytic)

Reference: CHI-MF-120SCF

€0.00 (tax incl.)

Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival,...

IL-4 (mouse) (rec.) (His)

Reference: CHI-MR-10004

€0.00 (tax incl.)

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...

IL-22 (mouse) (rec.) (His)

Reference: CHI-MR-10022

€0.00 (tax incl.)

Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1...

HMGB1 (rat):Fc (human) (rec.)

Reference: CHI-RF-311HMGB1

€0.00 (tax incl.)

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as...

IL-2 (rat) (rec.) (His)

Reference: CHI-RR-30002

€0.00 (tax incl.)

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...

CTRP3 (rat) (rec.) (His)

Reference: CHI-RR-300CTRP3

€0.00 (tax incl.)

CTRP3 (C1qTNF-related protein 3) plays an important role in regulating both embryonic cartilage development and postnatal longitudinal bone growth. CTRP3 stimulation leads to ERK1/2-dependent cell proliferation in...

HMGB1 (rat) (rec.) (His)

Reference: CHI-RR-300HMGB1

€0.00 (tax incl.)

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as...

Nuclease P1 (from Penicillium citrinum)

Reference: JAI-OPNUCP1

€0.00 (tax incl.)

Catalyzes the nonspecific endonucleolytic cleavage of single stranded DNA and RNA to yield nucleoside 5′-phosphates and 5′-phospho-oligonucleotides. Nuclease P1 hydrolyzes both 3'-5'-phosphodiester bonds in RNA and...

Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (untagged)

Reference: SBB-CE0011

€0.00 (tax incl.)

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an...

UBE2D3 [UbcH5c ] (human) (rec.) (untagged)

Reference: SBB-CE0019

€0.00 (tax incl.)

UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a...

UBE2L3 [UbcH7] (human) (rec.) (untagged)

Reference: SBB-CE0020

€0.00 (tax incl.)

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester...

UBE2D1 [UbcH5a] (human) (rec.) (untagged)

Reference: SBB-CE0021

€0.00 (tax incl.)

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a...

UBE2K [UbcH1, E2-25K] (human) (rec.) (His)

Reference: SBB-CE0022

€0.00 (tax incl.)

UBE2K (UbcH1) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2K via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub...

UBE2D2 [UbcH5b] (human) (rec.) (untagged)

Reference: SBB-CE0027

€0.00 (tax incl.)

UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a...

Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)

Reference: SBB-CE0058

€0.00 (tax incl.)

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an...

UcH-L3 (human) (rec.) (untagged)

Reference: SBB-DE0023

€0.00 (tax incl.)

UCHL3 (Ubiquitin C-terminal Hydrolase L3) is a deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease...

PLpro (SARS Coronavirus) (rec.) (His)

Reference: SBB-DE0024

€0.00 (tax incl.)

The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is...

NEDP1 [SENP8] (human) (rec.) (His)

Reference: SBB-DE0025

€0.00 (tax incl.)

NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which...

SENP1 (catalytic domain) (human) (rec.) (His)

Reference: SBB-DE0026

€0.00 (tax incl.)

SUMO/Sentrin Specific Peptidase 1 (SENP1) is a member of the SENP family of proteases, which belong to the group of cysteine-type peptidases. SENP1 is a SUMO-specific enzyme that catalyzes two essential functions....

20S Immunoproteasome (human) (untagged)

Reference: SBB-PP0004

€0.00 (tax incl.)

The 20S immunoproteasome is structurally similar to constitutive 26S proteasome. The 20S core of immunoproteasome contains two outer rings composed of alpha-subunits, and two internal 7-subunit containing rings each...

20S Proteasome (human) (untagged)

Reference: SBB-PP0005

€0.00 (tax incl.)

The ubiquitin-proteasome pathway is the major proteolytic system in eukaryotic cells, where it catalyzes the selective degradation of short-lived regulatory proteins or the rapid turnover of misfolded proteins. One of...

Category: Protein

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