Proteins & Peptides (4)

RO27-3225 TFA

Reference: HY-P2242A

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RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC50 of 1 nM and 8 nM for MC4R and MC1R, respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R. RO27-3225 TFA...

hCT(18-32)

Reference: HY-P4079

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hCT(18-32) is a hCT (human calcitonin)-derived peptide.

FMRF

Reference: HY-P0293

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FMRF is a peptide consisting of 4 amino acid residues.

Proadrenomedullin (45-92), human

Reference: HY-P1838

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Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45–92 of pre-proADM. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and...

SNAP-25 (187-203)

Reference: HY-P1820

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SNAP-25 (187-203), a peptide corresponding to residues 187–203 of SNAP-25, is a substrate for botulinum neurotoxin (BoNT)/A and can be used as a substrate for quantifying the activity of BoNT/C1(1-430) .

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid

Reference: HY-W040686

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2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid is a Glycine (HY-Y0966) derivative.

Endothelin-1 (1-31) (Human)

Reference: HY-P4159

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Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) is derived from the selective hydrolysis of big ET-1 by chymase.

HBV Seq1 aa:63-71

Reference: HY-P4049

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HBV Seq1 aa:63-71 is the fragment of hepatitis B virus (HBV).

β-CGRP, human

Reference: HY-P1548

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β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1...

Novokinin TFA

Reference: HY-P0080A

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Novokinin TFA is a peptide agonist of the angiotensin AT2 receptor.

Nangibotide TFA

Reference: HY-P3211A

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Nangibotide TFA is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide TFA can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia-reperfusion.

(2R,3S)-3-Phenylisoserine hydrochloride

Reference: HY-N2378

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(2R,3S)-3-Phenylisoserine hydrochloride is a serine derivative.

RGD peptide (GRGDNP)

Reference: HY-P1740

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RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through...

Z-D-Lys-OH

Reference: HY-W013297

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Z-D-Lys-OH is a lysine derivative.

N-terminally acetylated Leu-enkephalin

Reference: HY-P1170

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N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

Motixafortide

Reference: HY-P0171

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Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ～1 nM.

Fmoc-Ser(Trt)-OH

Reference: HY-W010734

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Fmoc-Ser(Trt)-OH is a serine derivative.

Cyclo(RGDfK(Mal))

Reference: HY-P4047

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Cyclo(RGDfK(Mal)) is a pentapeptide. Cyclo(RGDfK(Mal)) improves the attachment and infiltration of human pluripotent stem cells. Cyclo(RGDfK(Mal)) can be used for 3D stem cell culture and expansion.

H-D-Tyr-OEt.HCl

Reference: HY-W013406

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H-D-Tyr-OEt.HCl is a tyrosine derivative.

Mastoparan X

Reference: HY-P2705

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Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C...

Myelin Basic Protein(87-99)

Reference: HY-P1052

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Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is...

TAT-cyclo-CLLFVY

Reference: HY-P1420

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TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM.

SYNV-cyclo(CGGYF) TFA

Reference: HY-P4820A

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SYNV-cyclo(CGGYF) TFA is a Staphylococcus hominis (S. hominis) C5 autoinducing peptide. SYNV-cyclo(CGGYF) TFA inhibits S. aureus activity. SYNV-cyclo(CGGYF) TFA has the potential for the research of S. aureus-mediated...

pm26TGF-β1 peptide

Reference: HY-P2294

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pm26TGF-β1 peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide displays potent anti-inflammatory properties and...

H-Hyp(tBu)-OH

Reference: HY-W053531

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H-Hyp(tBu)-OH is a proline derivative.

L17E

Reference: HY-P4121

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L17E, an endosomolytic peptide, is a cationic amphiphilic peptide with specific membrane lytic activity for late endosomes (LEs). L17E diminishes the TS5-p45 induced apoptosis in a dose-dependent manner. L17E is...

(D)-PPA 1

Reference: HY-P4072

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(D)-PPA 1 is a hydrolysisresistant d-peptide antagonist. (D)-PPA 1 serves as a potent PD-1/PD-L1 inhibitor. (D)-PPA 1 binds to PD-1 with the affinity 0f 0.51 μM with in vitro and in vivo efficacy.

H-His(Trt)-OH

Reference: HY-W013155

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H-His(Trt)-OH is a histidine derivative.

Amyloid 17-42

Reference: HY-P3779

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Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein...

APETx2 TFA

Reference: HY-P1346A

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APETx2 TFA, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC50 of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2...

Mca-Glu-Asp-Ala-Ser-Thr-Pro-Cys-OH

Reference: HY-P4022

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Mca-Glu-Asp-Ala-Ser-Thr-Pro-Cys-OH is a L-Cysteine (HY-Y0337) derivative.

Erepdekinra

Reference: HY-P3450

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Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist.

CRF, bovine

Reference: HY-P1533

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CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.

AC-Asp(OtBU)-OH

Reference: HY-W024554

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AC-Asp(OtBU)-OH is an aspartic acid derivative.

ATI-2341 TFA

Reference: HY-P0172A

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ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory...

(4S)-1-Boc-4-amino-D-proline

Reference: HY-W019205

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(4S)-1-Boc-4-amino-D-proline is an amino acid derivative that can be used for compound synthesis.

Thymus Factor

Reference: HY-P3963

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Thymus Factor is a key factor responsible for the maturation of humoral immunological faculty.

N-Methyl-D-valine

Reference: HY-20561A

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N-Methyl-D-valine is a valine derivative.

Hemopressin (human, mouse)

Reference: HY-P1091

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Hemopressin is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB1 cannabinoid receptors....

Acetyl-Calpastatin(184-210)(human)

Reference: HY-P1081

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Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively.

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine

Reference: HY-W013793

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(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine is a serine derivative.

Epinecidin-1 TFA

Reference: HY-P2316

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Epinecidin-1 TFA is a multi-functional antimicrobial peptide (AMP) from Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has antibacterial, antifungal, antiviral, anti-tumor, and immunomodulatory...

Lixisenatide acetate

Reference: HY-P0119A

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Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).

H-Ala-Ala-Tyr-OH

Reference: HY-129028

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H-Ala-Ala-Tyr-OH can be synthesized mutant peptides.

HAEGTFTSD

Reference: HY-P1226

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HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide (HY-P0054A). GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretionin a glucose-dependant manner

Deltakephalin

Reference: HY-P2572

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Deltakephalin is a potent, selective opiate δ-receptor agonist. Deltakephalin has analgesic properties.

Caloxin 2A1

Reference: HY-P3278

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Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase.

Fibrinopeptide B, human TFA

Reference: HY-P1493A

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Fibrinopeptide B, human TFA (FPB,human TFA), human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

(2S)-Methyl 2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate

Reference: HY-I0102

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(2S)-Methyl 2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate is a valine derivative.

MIF-1

Reference: HY-107663

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MIF-1 (Melanostatin), an endogenous brain peptide, is a potent dopamine receptor allosteric modulator. MIF-1 inhibits melanin formation. MIF-1 blocks the effects of opioid receptor activation to modulate the analgesic...

HS024

Reference: HY-P1215

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HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake.

Angiotensin II 5-valine

Reference: HY-P0108

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Angiotensin II 5-valine is an agonist of angiotensin receptor.

Osteocalcin (1-49) (human)

Reference: HY-P2588

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Osteocalcin (1-49) (human) is a vitamin K-dependent bone specific protein. Osteocalcin (1-49) (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces.

Peptide T

Reference: HY-P0272

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Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.

H-Cys(pMeOBzl)-OH

Reference: HY-W012075

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H-Cys(pMeOBzl)-OH is a cysteine derivative.

Neuropeptide Y, porcine TFA

Reference: HY-P0212A

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Neuropeptide Y, porcine TFA, a peptide in porcine brain, is capable of inhibiting secretin-stimulated pancreatic secretion.

FOXO4-DRI acetate

Reference: HY-P4157A

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FOXO4-DRI acetate is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI acetate is a senolytic peptide that induces apoptosis of senescent cells.

[Tyr11]-Somatostatin

Reference: HY-P3062

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[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology.

Defensin HNP 4

Reference: HY-P3979

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Defensin HNP 4 (HNP 4) is a single 11 amino acid long fragment of HNP-41-11. Defensin HNP 4 has inhibitory effect against multidrug-resistant and non-resistant strains.

(Arg)9

Reference: HY-P0133

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(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.

(2R,2'R)-4,4'-Disulfanediylbis(2-aminobutanoic acid)

Reference: HY-77802

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(2R,2'R)-4,4'-Disulfanediylbis(2-aminobutanoic acid) is a cysteine derivative.

T-kinin

Reference: HY-P3543

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T-kinin (Ile-Ser-bradykinin) is a peptide containing bradykinin. T-kinin can be used for the research of inflammation.

Fmoc-Phe(2-Br)-OH

Reference: HY-W010825

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Fmoc-Phe(2-Br)-OH is a phenylalanine derivative.

H-Ser(tBu)-OtBu.HCl

Reference: HY-W013373

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H-Ser(tBu)-OtBu.HCl is a serine derivative.

TAT (47-57) GGG-Cys(Npys)

Reference: HY-P4123

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TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research.

β-Amyloid (1-9)

Reference: HY-P1854

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β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the...

Streptavidin

Reference: HY-P3152

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Streptavidin is a ∼60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent...

α-Conotoxin M I

Reference: HY-P3653

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α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. α-Conotoxins are small, disulfide-rich peptides that competitively inhibit...

Gp100 (619-627) (acetate)

Reference: HY-P1796A

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Gp100 (619-627) acetate is amino acids 619 to 627 fragment of human melanoma antigen glycoprotein 100 (gp100). Gp100 has been a widely studied target for melanoma immunotherapy.

Angiopeptin TFA

Reference: HY-P2090A

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Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth...

(S)-2-(2-Aminopropanamido)acetic acid

Reference: HY-W010277

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(S)-2-(2-Aminopropanamido)acetic acid is a Glycine (HY-Y0966) derivative.

RNAENFDRF

Reference: HY-P3429

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RNAENFDRF (βIIPKC624-632) is conjugated to the cell permeable peptide TAT47-57, which can be used to form an inhibitory peptide SAMβA. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association....

4-Methyl-L-leucine

Reference: HY-79415

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4-Methyl-L-leucine is a Glycine (HY-Y0966) derivative.

Ornipressin

Reference: HY-P0083

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Ornipressin is a potent vasoconstrictor, hemostatic and renal agent.

Histone H3 (21-44)

Reference: HY-P2556

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Histone H3 (21-44), derived from histone H3 21-44 amino acids, is usually used as a substrate (such as protein arginine methyltransferases) for methylation assays.

Boc-2-Nal-OH

Reference: HY-W011321

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Boc-2-Nal-OH is an alanine derivative.

MPS-Gαi3

Reference: HY-P4131

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MPS-Gαi3 is a cell penetrating peptide that can be used for drug delivery.

Pancreatic Polypeptide, bovine

Reference: HY-P1537

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Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine...

N-(Methylsulfonyl)glycine

Reference: HY-W141922

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N-(Methylsulfonyl)glycine is a Glycine (HY-Y0966) derivative.

γ-Glutamylhistidine

Reference: HY-P5097

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γ-Glutamylhistidine is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein...

Hsp70-derived octapeptide

Reference: HY-P1896

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Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs.

[D-Ala2]-Met-Enkephalin

Reference: HY-P2626

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[D-Ala2]-Met-Enkephalin, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalin inhibits ACh-induced and suckling-induced oxytocin (OT) release.

Neuromedin N

Reference: HY-P0079

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Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.

[D-Trp2,7,9] Substance P

Reference: HY-P3802

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[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively.

(S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid

Reference: HY-W011280

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(S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid is a phenylalanine derivative.

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid

Reference: HY-Y0134

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(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid is a glutamic acid derivative.

Boc-Phe(3-Br)-OH

Reference: HY-W041866

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Boc-Phe(3-Br)-OH is a phenylalanine derivative.

H-Lys(Tfa)-OH

Reference: HY-W012064

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H-Lys(Tfa)-OH is a lysine derivative.

Ac-VDVAD-AFC

Reference: HY-P2615

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Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer.

TAT-14

Reference: HY-P1328

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TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1.

Cyclo(L-Trp-L-Trp)

Reference: HY-P2124

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Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae,...

NS2 (114-121), Influenza

Reference: HY-P2521

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NS2 (114-121), Influenza, the 114-121 fragment of influenza nonstructural protein 2 (NS2), is a influenza-derived epitope. NS2 (114-121), Influenza can be used for the research of CD8+ cytotoxic T lymphocyte (CTL) in...

GnRH Associated Peptide (25-53), human

Reference: HY-P3605

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GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and...

Cyclic nona-L-arginine TFA

Reference: HY-P3193

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Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts.

LL-37, human

Reference: HY-P1222

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LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates...

H-DL-Phe-OtBu.HCl

Reference: HY-W052408

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H-DL-Phe-OtBu.HCl is a phenylalanine derivative.

α2β1 Integrin Ligand Peptide TFA

Reference: HY-P1868A

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α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

GR 94800 TFA

Reference: HY-P1277A

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GR 94800 TFA is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively.

2-Fluoro-L-phenylalanine

Reference: HY-W016336

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2-Fluoro-L-phenylalanine is a phenylalanine derivative.

Fmoc-Thr(TBDMS)-OH

Reference: HY-W048671

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Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted research.

Category: Proteins & Peptides

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