Proteins & Peptides (35)

Recombinant human 26S proteasome non-ATPase regulatory subunit 4/S5A/PSMD4 protein

Reference: RP10165LQ

€0.00 (tax incl.)

S5a is one of the integral Ub receptors of the 26S proteasome. It’s N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs)...

Recombinant human SUMO-2 (Q90P) protein

Reference: RP10168LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human SUMO-3 protein

Reference: RP10170LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human Ubiquitin(K0) protein

Reference: RP10176LQ

€0.00 (tax incl.)

All lysine residues in Ub(K0) were substituted with arginine residues, thereby Ub(K0) can only support monoubiquitination, but not polyubiquitination.

Recombinant human Ubiquitin(K11R) protein

Reference: RP10177LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K27R) protein

Reference: RP10178LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K29R) protein

Reference: RP10179LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K63R) protein

Reference: RP10182LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(S20C) protein

Reference: RP10185LQ

€0.00 (tax incl.)

Ubiquitin (S20C) bears a single amino acid substitution that replaces serine 20 with a cysteine. This substitution has no effect on Ub’s structure and allows label Ub with other groups, such as biotin or fluorescent...

Recombinant human Ubiquitin(1-75) protein

Reference: RP10186LQ

€0.00 (tax incl.)

Ub75 lacks the amino acid glycine 76, which is required to form thioester bond with Ub activating enzyme E1. Therefore, Ub75 can not react with E1, E2 and E3 enzymes; and does not support ubiquitination. It can be...

Recombinant human Ubiquitin thioesterase L1/UCHL1 protein

Reference: RP10187LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin thioesterase L3/UCHL3 protein

Reference: RP10188LQ

€0.00 (tax incl.)

Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has...

26S proteasome

Reference: RP10189TLQ

€0.00 (tax incl.)

The 26S proteasome is an approximately 2.5 mDa large complex composed of the 20S proteasome and the 19S regulatory particle (also called PA700 in mammals). The 20S proteasome has 28 subunits that form a barrel –...

19S proteasome/PA700

Reference: RP10190TLQ

€0.00 (tax incl.)

The 19S regulatory particle (PA700) locates on either one or both ends of the 20S core particle of the 26S proteasome. It has 19 subunits including six AAA ATPases that associate with α subunits of the 20S proteasome...

immuno 20S proteasome

Reference: RP10192TLQ

€0.00 (tax incl.)

Upon stimulation with IFN – γ, the expression of the three catalytic β subunits β1, β2, and β5 with iso-forms β1i (LMP2), β2i (MECL – 1), and β5i (LMP7) are induced, respectively. These subunits are incorporated into...

Recombinant human Ubiquitin-activating enzyme E1/UBE1/UBA1 protein

Reference: RP10193LQ

€0.00 (tax incl.)

UBE1 is an E1 enzyme within the E1, E2, E3 cascade which conjugates Ub to protein substrates. UBE1 activates Ub by catalyzing an ATP – dependent reaction; Ub is conjugated onto the catalytic cysteine residue of UBE1...

K29-linked diUb

Reference: RP10197D

€0.00 (tax incl.)

This product is a native K29-linked diUb which can be used as a substrate of deubiquitinating enzyems. It can also be used to investigate linkage specificity of proteins that contain ubiquitin-associated domains or...

K33-linked diUb

Reference: RP10198D

€0.00 (tax incl.)

This product is a native K33-linked diUb which can be used as a substrate for deubiquitinating enzymes. It can also be used to investigate linkage specificity of proteins that contain ubiquitin-associated domains or...

N-terminal TAMRA-Ubiquitin

Reference: RP10200DLQ

€0.00 (tax incl.)

N-terminal TARMA-Ub (also called TARMA-Ub) is a fluorescent Ub, in which TAMRA (5-tetramethylrhodamine) is covalently conjugated on the N-terminus of Ub. All seven lysine residues in TARMA-Ub are available for...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 7/USP7 protein

Reference: RP10202LQ

€0.00 (tax incl.)

USP7 is a cysteine protease, belongs to the family of ubiquitin-specific proteases. USP7 was first discovered as a binding enzyme to the Herpes simplex viral protein. Studies have shown that USP7 could deubiquitinate...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 11/USP11 protein

Reference: RP10203LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 16 protein

Reference: RP10204LQ

€0.00 (tax incl.)

USP16 is an active deubiquitinating enzyme (DUB) encoded on chromosome 21, trisomy of which causes Down’s syndrome (DS). USP16 is a phosphoprotein, phosphorylation of USP16 controls its cellular localization, but no...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 35/USP35 protein

Reference: RP10205LQ

€0.00 (tax incl.)

USP35 is a 1018 amino acid cysteine DUB that was found to be overexpressed in certain breast cancers. Its USP domain ranges from amino acids 425 to 926, with cysteine 450 as the catalytic cysteine residue.

E2 Screening Kit

Reference: RP10206K

€0.00 (tax incl.)

The E2 Screening Kit is developed for identification of the E2 Ub-conjugating enzyme(s) for a specific E3 Ub ligase and/or a protein substrate. This kit contains 29 E2 enzymes.

Di-ubiquitin Explorer Kit

Reference: RP10208K

€0.00 (tax incl.)

This kit contains 5 μg each of linear, K6, K11, K27, K29, K33, K48, and K63-linked diubiquitin, a total of eight different diubiquitin forms. It can be used for determining linkage specificity of deubiquitinating...

K48 polyUb Chain-binding Protein Identification / Validation Kit

Reference: RP10209K

€0.00 (tax incl.)

This kit is designed for two purposes: 1) identification of proteins that specially bind K48 polyUb chains in whole cell or tissue lysates; 2) validation of direct interactions between K48 polyUb chains and their...

K63 polyUb Chain-binding Protein Identification / Validation Kit

Reference: RP10210K

€0.00 (tax incl.)

This kit is designed for two purposes: 1) identification of proteins that specially bind K63 polyUb chains in whole cell or tissue lysates; 2) validation of direct interactions between K63 polyUb chains and their...

Sumo2 Conjugation Kit

Reference: RP10213K

€0.00 (tax incl.)

Sumo2 Conjugation Kit is designed for assaying the conjugation of Sumo2 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo activating enzyme SAE1/SAE2 (E1)...

Sumo3 Conjugation Kit

Reference: RP10214K

€0.00 (tax incl.)

Sumo3 Conjugation Kit is designed for assaying the conjugation of Sumo3 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo activating enzyme SAE1/SAE2 (E1)...

Sumo1, Sumo2, Sumo 3 Conjugation Kit

Reference: RP10215K

€0.00 (tax incl.)

Sumo1, Sumo2, Sumo 3 Conjugation Kit is designed for assaying the conjugation of Sumo1, Sumo2 and Sumo3 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo...

Ubiquitin Linkage Screening Kit II

Reference: RP10218K

€0.00 (tax incl.)

Ubiquitin Linkage Screening Kit II is designed for two purposes: 1) to identify the ubiquitin lysine residue that is used to link the polyubiquitin chain conjugated on a protein substrate; 2) to determine whether a...

Proteasome Activity Fluorometric Assay Kit I

Reference: RP10220K

€0.00 (tax incl.)

Proteasome Activity Fluorometric Assay Kit I is designed for assaying the proteasome’s chymotrypsin-like activity in vitro using purified proteasome, cleared cell lysates or tissue extracts. The proteasome cleaves...

Proteasome Activity Fluorometric Assay Kit II

Reference: RP10221K

€0.00 (tax incl.)

Proteasome Activity Fluorometric Assay Kit II is designed for assaying the proteasome’s chymotrypsin-like, trypsin-like and caspase-like activities in vitro using purified proteasome, cleared cell lysates or tissue...

Immunoproteasome Activity Fluorometirc Assay Kit I

Reference: RP10222K

€0.00 (tax incl.)

Immunoproteasome Activity Fluorometric Assay Kit I was designed for assaying the immunoproteasomes'' chymotrypsin-like activity in vitro using purified proteasome, cell lysates or tissue extracts. The proteasome...

Rapid 26S Proteasome Purification Kit-L

Reference: RP10225K

€0.00 (tax incl.)

The Rapid 26S Proteasome Purification Kit is designed to rapidly purify the endogenous 26S proteasome from cell or tissue extracts within 8 hours according to a published method (reference 1) with modifications. This...

26S Proteasome-mediated Protein Degradation Kit

Reference: RP10226K

€0.00 (tax incl.)

This kit is designed for assaying 26S proteasome-mediated degradation of ubiquitinated proteins in vitro. It contains highly purified active bovine 26S proteasome that has been used by different research groups for...

K63 Polyubiquitin Chain Capture Kit

Reference: RP10230K

€0.00 (tax incl.)

This kit is designed for enrichment of polyubiquitinated cellular proteins conjugated with lysine 63 using GST-TAB2 (NZF). Polyubiquitinated proteins bound on GST-TAB2 (NZF) can be precipitated using glutathione resin...

Linear Polyubiquitin Chain Capture Kit

Reference: RP10231K

€0.00 (tax incl.)

This kit is designed for enrichment of cellular proteins conjugated with linear polyubiquitin chains using GST-NEMO (UBAN). Polyubiquitinated proteins bound on GST-NEMO (UBAN) can be precipitated using glutathione...

Polyubiquitin Chain Capture Kit

Reference: RP10232K

€0.00 (tax incl.)

This kit is designed for enrichment of polyubiquitinated cellular proteins using GST tagged recombinant proteins that bind lysine 48 and lysine 63 polyubiquitin chains. It can be used to enrich polyubiquitinated...

Deubiquitinating Enzyme (DUB) Identification Kit

Reference: RP10237K

€0.00 (tax incl.)

This kit is designed to enrich deubiquitinating enzymes in crude or partially purified cell/tissue extracts, followed by identification using immunoblotting or mass spectrometry.

Caspase-3, 7 Activity Fluorometric Assay Kit

Reference: RP10240K

€0.00 (tax incl.)

Caspase-3, 7 Activity Fluorometric Assay Kit can be used for assaying caspase-3, 7 activities in cell/tissue extracts in a 96-well plate format. Each of the supplied fluorogenic substrate and the pan caspase inhibitor...

Ubiquitin aldehyde/Ubal

Reference: RP10241DLQ

€0.00 (tax incl.)

Ub aldehyde is a potent and highly specific inhibitor of cysteine deubiquitinating enzymes including the Ub C-terminal hydrolases (UCHs), the Ub-specific proteases (USPs), the ovarian tumor domains (OTUs) proteases...

HA-Ub-VME

Reference: RP10242D

€0.00 (tax incl.)

A potent, irreversible and specific inhibitor of deubiquitinating enzymes (DUBs) that is prepared by chemical synthesis. It is N-terminally tagged with an HA-tag (YPYDVPDYA), which allows for sensitive identification...

Biotin-Ub-PA

Reference: RP10243D

€0.00 (tax incl.)

Biotin-Ub-PA is a newly developed potent and specific inhibitor of deubiquitinating enzymes (DUBs), which has a N-terminal biotin tag. An aminohexanoic acid (Ahx) linker is used to create extra space between the...

Cy5-Ub-VME

Reference: RP10245D

€0.00 (tax incl.)

Cy5-Ub-VME is a potent, irreversible and specific inhibitor of deubiquitinating enzymes (DUBs), which is labeled on the N-terminus with a Cy5 dye (Cy5, Ex 625-650 nm, Em 670 nm). This ubiquitin-based activity probe...

biotin-SUMO2-VME

Reference: RP10246D

€0.00 (tax incl.)

A potent, irreversible and specific inhibitor of deSUMOylation proteases (SENPs) that cleave SUMO2 conjugates. It is N-terminally tagged with a biotin, which allows for sensitive identification of SENPs using...

Ub-Rhodamine110

Reference: RP10248DLQ

€0.00 (tax incl.)

Ub-Rhodamine 110 is a quenched, fluorescent substrate for deubiquitinating enzymes. Cleavage of the amide bond between the C-terminal glycine of ubiquitin and rhodamine110 results in an increase in rhodamine...

Recombinant SARS-CoV Spike S1+S2 ECD(S-ECD) Protein

Reference: RP01298LQ

€0.00 (tax incl.)

Recombinant human Ubiquitin thioesterase ZRANB1 protein

Reference: RP10005LQ

€0.00 (tax incl.)

TRABID is an OUT domain-containing deubiquitinating enzyme that exhibits specificity to K29/K33-linked polyubiquitin chains. 6xHis-GST-TRABID(NZF1) contains the N-terminal NZF1 domain (amino acid 1-33) of TRABID fused...

Recombinant human Proteasome inhibitor PI31 subunit protein

Reference: RP10021LQ

€0.00 (tax incl.)

PI31 is a proline-rich protein and its C-terminal region can act as a potent 20S proteasome inhibitor in vitro. In cells, it plays a role in regulating 26S proteasome assembly and activity.

Recombinant human SENP1 (catalytic domain) protein

Reference: RP10024LQ

€0.00 (tax incl.)

SUMO1-3 (small ubiquitin-related modifiers) are ubiquitin-like proteins that can be conjugated to substrate proteins using a cascade of enzymatic reactions. Protein sumoylation can be reversed by the sentrin-specific...

Recombinant human Ubiquitin-conjugating enzyme E2 S/UBE2S(1-156) protein

Reference: RP10058LQ

€0.00 (tax incl.)

UbE2S is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. UbE2S works with the Ub ligase, anaphase-promoting complex (APC/C), to ubiquitinate proteins...

Recombinant human Ubiquitin (K48R) protein

Reference: RP10077LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 14 protein

Reference: RP10085LQ

€0.00 (tax incl.)

Usp14 is one of the deubiquitinating enzymes of the human 26S proteasome. Usp14 belongs to the Ub-specific proteases family. Usp14 catalyzes Ub chain trimming that shortens a polyUb chain from the distal end of the Ub...

Recombinant human ADRM1&UCH-L5 protein

Reference: RP10087LQ

€0.00 (tax incl.)

Adrm1 is an integral Ub receptor of the 26S proteasome. Adrm1 binds both Ub and polyUb chains via its N-terminal Pru domain. The Pru domain also binds S1 to locate Adrm1 on the 26S proteasome. The C-terminal domain...

Recombinant human Fluorescein labeled K48-Ub(2-10) protein

Reference: RP10092LQ

€0.00 (tax incl.)

This product contains authentic K48-linked isopeotide bonds, synthesized by an enzymatic reaction containing UbE1, GST-E2-25K and fluorescein-Ub (catalog # E1155/E1156). Mainly contain Ub(2-10) chains with residual...

Recombinant human Deubiquitinase DESI2 protein

Reference: RP10100LQ

€0.00 (tax incl.)

DESI-2 (desumoylating isopeptidase 2, also called Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes (PPPDE1)) and DESI-1 (also called PPPDE2) contain a Ub-binding domain and a cysteine protease domain....

Recombinant human Atrophin-1 interacting protein 4/ITCH protein

Reference: RP10137LQ

€0.00 (tax incl.)

ITCH, also called atrophin-1 interacting protein 4 (AIP4), is a HECT-type E3 ubiquitin ligase. It contains an N-terminal Ca

Recombinant human K11-Ub2 protein

Reference: RP10139LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K63-Ub4 protein

Reference: RP10149LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human TNF-alpha protein

Reference: RP10171LQ

€0.00 (tax incl.)

TNFalpha (Tumor necrosis factor alpha) is produced by immune and epithelial cells. It plays important roles in regulating inflammation, apoptosis, and immune response. It exerts its function mainly by binding of two...

Recombinant human Ubiquitin protein

Reference: RP10173LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(+1) protein

Reference: RP10174LQ

€0.00 (tax incl.)

Ubiquitin (+1) consists of the first 75 amino acids of ubiquitin, but lacks glycine 76 because of the deletion of two of the three nucleotides that encode glycine 76. The resulting frame shift leads to the addition of...

20S proteasome

Reference: RP10191TLQ

€0.00 (tax incl.)

The 20S proteasome has a barrel – shaped structure arranged as four heptomeric rings of αββα. In eukaryotes, each of α and β ring is composed of seven different proteins. The β1, β2 and β5 subunits have...

K6-linked diUb

Reference: RP10195D

€0.00 (tax incl.)

This product is a native K6-linked diUb which can be used as a substrate for deubiquitinating enzymes. It can also be used to investigate linkage specificiy of proteins that contain ubiquitin-associated domains or...

N-terminal Biotin-Ubiquitin

Reference: RP10199DLQ

€0.00 (tax incl.)

A single biotin moiety is conjugated on the N-terminus of ubiquitin. All lysine residues of ubiquitin are still available for formation of polyubiquitin chains. The extremely high binding affinity between biotin and...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 7/USP7 protein

Reference: RP10201LQ

€0.00 (tax incl.)

USP7 is a cysteine protease, belongs to the family of ubiquitin-specific proteases. USP7 was first discovered as a binding enzyme to the Herpes simplex viral protein. Studies have shown that USP7 could deubiquitinate...

Linear polyUb Chain-binding Protein Identification / Validation Kit

Reference: RP10211K

€0.00 (tax incl.)

This kit is designed for two purposes: 1) identification of proteins that specially bind linear polyUb chains in whole cell or tissue lysates; 2) validation of direct interactions between linear polyUb chains and...

Immunoproteasome Activity Fluorometirc Assay Kit II

Reference: RP10223K

€0.00 (tax incl.)

Immunoproteasome Activity Fluorometric Assay Kit II was designed for assaying the immunoproteasomes' chymotrypsin-like, trypsin-like and caspase-like activities in vitro using purified proteasomes, cell lysates or...

K29/K33 polyubiquitin Chain Capture Kit

Reference: RP10233K

€0.00 (tax incl.)

This kit is designed for enrichment of cellular proteins conjugated with lysine 29/33-linked polyubiquitin chains using GST-TRABID (ZNF1). Polyubiquitinated proteins bound on GST-TRABID (ZNF1) can be precipi-tated...

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