Category: Proteins & Peptides

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GBP6 blocking peptide GBP6 blocking peptide

GBP6 blocking peptide

Reference: GTX17166-PEP
€0.00 (tax incl.)
Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 26 [PubMed 16689661]).[supplied by OMIM, Dec 28]
Angiopoietin 2 blocking peptide Angiopoietin 2 blocking peptide

Angiopoietin 2 blocking peptide

Reference: GTX17167-PEP
€0.00 (tax incl.)
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce...
WDR5 blocking peptide WDR5 blocking peptide

WDR5 blocking peptide

Reference: GTX17169-PEP
€0.00 (tax incl.)
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 4 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation...
PHOX2A blocking peptide PHOX2A blocking peptide

PHOX2A blocking peptide

Reference: GTX17170-PEP
€0.00 (tax incl.)
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous...
PTPRD blocking peptide PTPRD blocking peptide

PTPRD blocking peptide

Reference: GTX17171-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,...
SDHAF1 blocking peptide SDHAF1 blocking peptide

SDHAF1 blocking peptide

Reference: GTX17172-PEP
€0.00 (tax incl.)
The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for...
APBA1 blocking peptide APBA1 blocking peptide

APBA1 blocking peptide

Reference: GTX17173-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits...
RAB21 blocking peptide RAB21 blocking peptide

RAB21 blocking peptide

Reference: GTX17174-PEP
€0.00 (tax incl.)
RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2 [PubMed 1887961]).[supplied by OMIM, Nov 28]
VAMP7 blocking peptide VAMP7 blocking peptide

VAMP7 blocking peptide

Reference: GTX17175-PEP
€0.00 (tax incl.)
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and...
NDFIP1 blocking peptide NDFIP1 blocking peptide

NDFIP1 blocking peptide

Reference: GTX17176-PEP
€0.00 (tax incl.)
The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This...
Angiogenin blocking peptide Angiogenin blocking peptide

Angiogenin blocking peptide

Reference: GTX17177-PEP
€0.00 (tax incl.)
The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In...
BCAR3 blocking peptide BCAR3 blocking peptide

BCAR3 blocking peptide

Reference: GTX17178-PEP
€0.00 (tax incl.)
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer...
C/EBP delta blocking peptide C/EBP delta blocking peptide

C/EBP delta blocking peptide

Reference: GTX17179-PEP
€0.00 (tax incl.)
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The...
ACSL1 blocking peptide ACSL1 blocking peptide

ACSL1 blocking peptide

Reference: GTX17180-PEP
€0.00 (tax incl.)
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of...
GDF1 blocking peptide GDF1 blocking peptide

GDF1 blocking peptide

Reference: GTX17181-PEP
€0.00 (tax incl.)
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a...
FOXH1 blocking peptide FOXH1 blocking peptide

FOXH1 blocking peptide

Reference: GTX17182-PEP
€0.00 (tax incl.)
FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. [provided by RefSeq, Jul 28]
B7-H4 blocking peptide B7-H4 blocking peptide

B7-H4 blocking peptide

Reference: GTX17189-PEP
€0.00 (tax incl.)
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface...
Cyclin T1 blocking peptide Cyclin T1 blocking peptide

Cyclin T1 blocking peptide

Reference: GTX17200-PEP
€0.00 (tax incl.)
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b...
MIP1 beta blocking peptide MIP1 beta blocking peptide

MIP1 beta blocking peptide

Reference: GTX17201-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory...
HE4 blocking peptide HE4 blocking peptide

HE4 blocking peptide

Reference: GTX17207-PEP
€0.00 (tax incl.)
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a...
ERAP2 blocking peptide ERAP2 blocking peptide

ERAP2 blocking peptide

Reference: GTX17208-PEP
€0.00 (tax incl.)
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 66832) and LRAP to trim...
CD160 blocking peptide CD160 blocking peptide

CD160 blocking peptide

Reference: GTX17209-PEP
€0.00 (tax incl.)
CD16 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector...
GLIPR1 blocking peptide GLIPR1 blocking peptide

GLIPR1 blocking peptide

Reference: GTX17212-PEP
€0.00 (tax incl.)
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with...
ITCH blocking peptide ITCH blocking peptide

ITCH blocking peptide

Reference: GTX17213-PEP
€0.00 (tax incl.)
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting...
APOBEC3B blocking peptide APOBEC3B blocking peptide

APOBEC3B blocking peptide

Reference: GTX17214-PEP
€0.00 (tax incl.)
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode...
TRF2 blocking peptide TRF2 blocking peptide

TRF2 blocking peptide

Reference: GTX17215-PEP
€0.00 (tax incl.)
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of...
USP25 blocking peptide USP25 blocking peptide

USP25 blocking peptide

Reference: GTX17216-PEP
€0.00 (tax incl.)
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by...
POU2F3 blocking peptide POU2F3 blocking peptide

POU2F3 blocking peptide

Reference: GTX17217-PEP
€0.00 (tax incl.)
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded...
MFN1 blocking peptide MFN1 blocking peptide

MFN1 blocking peptide

Reference: GTX17218-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact...
ANGPTL3 blocking peptide ANGPTL3 blocking peptide

ANGPTL3 blocking peptide

Reference: GTX17219-PEP
€0.00 (tax incl.)
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil...
SHBG blocking peptide SHBG blocking peptide

SHBG blocking peptide

Reference: GTX17222-PEP
€0.00 (tax incl.)
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each...
SMURF1 blocking peptide SMURF1 blocking peptide

SMURF1 blocking peptide

Reference: GTX17223-PEP
€0.00 (tax incl.)
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell...
RHOG blocking peptide RHOG blocking peptide

RHOG blocking peptide

Reference: GTX17227-PEP
€0.00 (tax incl.)
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins...
Connexin 26 blocking peptide Connexin 26 blocking peptide

Connexin 26 blocking peptide

Reference: GTX17229-PEP
€0.00 (tax incl.)
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells....
FOXG1 blocking peptide FOXG1 blocking peptide

FOXG1 blocking peptide

Reference: GTX17231-PEP
€0.00 (tax incl.)
This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with...
PRRX1 blocking peptide PRRX1 blocking peptide

PRRX1 blocking peptide

Reference: GTX17237-PEP
€0.00 (tax incl.)
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity...
ADRM1 blocking peptide ADRM1 blocking peptide

ADRM1 blocking peptide

Reference: GTX17239-PEP
€0.00 (tax incl.)
The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be...
ARHI blocking peptide ARHI blocking peptide

ARHI blocking peptide

Reference: GTX17241-PEP
€0.00 (tax incl.)
This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal...
SPIB blocking peptide SPIB blocking peptide

SPIB blocking peptide

Reference: GTX17242-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found...
Relaxin 3 blocking peptide Relaxin 3 blocking peptide

Relaxin 3 blocking peptide

Reference: GTX17243-PEP
€0.00 (tax incl.)
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence...
RNF121 blocking peptide RNF121 blocking peptide

RNF121 blocking peptide

Reference: GTX17248-PEP
€0.00 (tax incl.)
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively...
GAPDH blocking peptide GAPDH blocking peptide

GAPDH blocking peptide

Reference: GTX17307-PEP
€0.00 (tax incl.)
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct...
Vinculin blocking peptide Vinculin blocking peptide

Vinculin blocking peptide

Reference: GTX17308-PEP
€0.00 (tax incl.)
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in...
RBM20 blocking peptide RBM20 blocking peptide

RBM20 blocking peptide

Reference: GTX17481-PEP
€0.00 (tax incl.)
This gene encodes a protein that likely binds RNA. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Mar 21]
Claudin 14 blocking peptide Claudin 14 blocking peptide

Claudin 14 blocking peptide

Reference: GTX19035-PEP
€0.00 (tax incl.)
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing...
Pericentrin 1 blocking peptide Pericentrin 1 blocking peptide

Pericentrin 1 blocking peptide

Reference: GTX19044-PEP
€0.00 (tax incl.)
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one...
USH1C blocking peptide USH1C blocking peptide

USH1C blocking peptide

Reference: GTX19045-PEP
€0.00 (tax incl.)
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST...
AKAP3 blocking peptide AKAP3 blocking peptide

AKAP3 blocking peptide

Reference: GTX19046-PEP
€0.00 (tax incl.)
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete...
HPS3 blocking peptide HPS3 blocking peptide

HPS3 blocking peptide

Reference: GTX19047-PEP
€0.00 (tax incl.)
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a...
Androgen Receptor blocking peptide Androgen Receptor blocking peptide

Androgen Receptor blocking peptide

Reference: GTX19066-PEP
€0.00 (tax incl.)
The androgen receptor gene is more than 9 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a...
TLR3 blocking peptide TLR3 blocking peptide

TLR3 blocking peptide

Reference: GTX20260-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila...
TRPM7 blocking peptide TRPM7 blocking peptide

TRPM7 blocking peptide

Reference: GTX20729-PEP
€0.00 (tax incl.)
The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and...
activated NOTCH1 peptide activated NOTCH1 peptide

activated NOTCH1 peptide

Reference: GTX20730
€0.00 (tax incl.)
This peptide can be used as a blocking peptide for the rabbit polyclonal to NOTCH1 (GTX28925).
MTA1 blocking peptide MTA1 blocking peptide

MTA1 blocking peptide

Reference: GTX20751-PEP
€0.00 (tax incl.)
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic...
BAIAP2 (isoform 3) blocking peptide BAIAP2 (isoform 3) blocking peptide

BAIAP2 (isoform 3) blocking peptide

Reference: GTX20791-PEP
€0.00 (tax incl.)
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This...
NFIL3 blocking peptide NFIL3 blocking peptide

NFIL3 blocking peptide

Reference: GTX21078-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and...
LASP1 (N Terminus) blocking peptide LASP1 (N Terminus) blocking peptide

LASP1 (N Terminus) blocking peptide

Reference: GTX21301-PEP
€0.00 (tax incl.)
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is...
CD20 (C Terminus) blocking peptide CD20 (C Terminus) blocking peptide

CD20 (C Terminus) blocking peptide

Reference: GTX21310-PEP
€0.00 (tax incl.)
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique...
Musculin blocking peptide Musculin blocking peptide

Musculin blocking peptide

Reference: GTX21330-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A...
PPP2R5B blocking peptide PPP2R5B blocking peptide

PPP2R5B blocking peptide

Reference: GTX21366-PEP
€0.00 (tax incl.)
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and...
Cortactin/EMS1 blocking peptide Cortactin/EMS1 blocking peptide

Cortactin/EMS1 blocking peptide

Reference: GTX21374-PEP
€0.00 (tax incl.)
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles:...
DDAH2 blocking peptide DDAH2 blocking peptide

DDAH2 blocking peptide

Reference: GTX21383-PEP
€0.00 (tax incl.)
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn...
Notch1 intra peptide Notch1 intra peptide

Notch1 intra peptide

Reference: GTX21390
€0.00 (tax incl.)
This peptide can be used as a blocking peptide for the rabbit polyclonal to Notch 1 (intra)- GTX28387.
RanGAP1 blocking peptide RanGAP1 blocking peptide

RanGAP1 blocking peptide

Reference: GTX22081-PEP
€0.00 (tax incl.)
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the...
PGAM1/PGAM2/PGAM4 blocking peptide PGAM1/PGAM2/PGAM4 blocking peptide

PGAM1/PGAM2/PGAM4 blocking peptide

Reference: GTX22220-PEP
€0.00 (tax incl.)
Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway...
PACSIN3 blocking peptide PACSIN3 blocking peptide

PACSIN3 blocking peptide

Reference: GTX22226-PEP
€0.00 (tax incl.)
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in...
GRB2 blocking peptide GRB2 blocking peptide

GRB2 blocking peptide

Reference: GTX22234-PEP
€0.00 (tax incl.)
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins,...
TMS1 blocking peptide TMS1 blocking peptide

TMS1 blocking peptide

Reference: GTX22236-PEP
€0.00 (tax incl.)
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains...
SIAH1 blocking peptide SIAH1 blocking peptide

SIAH1 blocking peptide

Reference: GTX22237-PEP
€0.00 (tax incl.)
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The...
TBL1X / TBL1XR1 blocking peptide TBL1X / TBL1XR1 blocking peptide

TBL1X / TBL1XR1 blocking peptide

Reference: GTX22243-PEP
€0.00 (tax incl.)
The protein encoded by this gene has sequence similarity with members of the WD4 repeat-containing protein family. The WD4 group is a large family of proteins, which appear to have a regulatory function. It is...
RAC2 blocking peptide RAC2 blocking peptide

RAC2 blocking peptide

Reference: GTX22244-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control...
PSCDBP blocking peptide PSCDBP blocking peptide

PSCDBP blocking peptide

Reference: GTX22247-PEP
€0.00 (tax incl.)
The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T...
Dysadherin blocking peptide Dysadherin blocking peptide

Dysadherin blocking peptide

Reference: GTX22248-PEP
€0.00 (tax incl.)
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids....
RACGAP1 blocking peptide RACGAP1 blocking peptide

RACGAP1 blocking peptide

Reference: GTX22270-PEP
€0.00 (tax incl.)
The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate...
DUSP10 blocking peptide DUSP10 blocking peptide

DUSP10 blocking peptide

Reference: GTX22272-PEP
€0.00 (tax incl.)
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily...
BAK blocking peptide BAK blocking peptide

BAK blocking peptide

Reference: GTX22273-PEP
€0.00 (tax incl.)
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...
COX1 blocking peptide COX1 blocking peptide

COX1 blocking peptide

Reference: GTX22338-PEP
€0.00 (tax incl.)
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal...
STAT6 peptide STAT6 peptide

STAT6 peptide

Reference: GTX22425
€0.00 (tax incl.)
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and...
Her2 / ErbB2 peptide Her2 / ErbB2 peptide

Her2 / ErbB2 peptide

Reference: GTX22429
€0.00 (tax incl.)
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it...
TRAIL peptide TRAIL peptide

TRAIL peptide

Reference: GTX22436
€0.00 (tax incl.)
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill...
Fas peptide Fas peptide

Fas peptide

Reference: GTX22438
€0.00 (tax incl.)
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death,...
APAF1 peptide APAF1 peptide

APAF1 peptide

Reference: GTX22446
€0.00 (tax incl.)
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-4 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c...
Diablo peptide Diablo peptide

Diablo peptide

Reference: GTX22450
€0.00 (tax incl.)
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor...
p107 peptide p107 peptide

p107 peptide

Reference: GTX22452
€0.00 (tax incl.)
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell...
FRAT2 blocking peptide FRAT2 blocking peptide

FRAT2 blocking peptide

Reference: GTX22470-PEP
€0.00 (tax incl.)
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor...
AIBZIP blocking peptide AIBZIP blocking peptide

AIBZIP blocking peptide

Reference: GTX22474-PEP
€0.00 (tax incl.)
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization...
ADAM8 blocking peptide ADAM8 blocking peptide

ADAM8 blocking peptide

Reference: GTX22475-PEP
€0.00 (tax incl.)
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been...

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