Proteins & Peptides (3)

VISTA [B7-H5] (mouse):Fc (human) (rec.)

Reference: AG-40B-0164

€0.00 (tax incl.)

Mouse VISTA is a 55- to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with...

IL-36alpha (aa 6-158) (human) (rec.) (untagged)

Reference: AG-40B-0165

€0.00 (tax incl.)

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines...

IL-36gamma (aa 18-169) (human) (rec.) (untagged)

Reference: AG-40B-0166

€0.00 (tax incl.)

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines...

IL-33 (oxidation resistant) (human) (rec.) (His)

Reference: AG-40B-0167

€0.00 (tax incl.)

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to...

Slit2 (C fragment) (human) (rec.)

Reference: AG-40B-0168

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The Slits are secreted proteins that bind to Robo receptors and play a role in axon guidance and neuronal migration. The Slit family in mice and humans comprises three members: Slit1, Slit2 and Slit3. These are all...

IL-38 (aa 20-152) (human) (rec.) (His)

Reference: AG-40B-0169

€0.00 (tax incl.)

IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a...

CD112R (mouse):Fc (human) (rec.)

Reference: AG-40B-0170

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CD112 (also called Nectin-2 or poliovirus receptor-related 2 protein) is a type I transmembrane glycoprotein and a member of the Ig gene superfamily (IGSF). CD112/Nectin-2 functions as an adhesion molecule involved in...

Fc (human):OX40L, Soluble (human) (rec.)

Reference: AG-40B-0172

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OX40L [CD252; TNFSF4] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its receptor OX40 on T cells, stimulating T cell activation, proliferation...

Fc (human):CD137L, Soluble (human) (rec.)

Reference: AG-40B-0173

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The CD137 ligand (CD137L; 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction...

DLL4 (human):Fc (human) (rec.) (highly active mutant)

Reference: AG-40B-0176

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The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative...

VISTA [B7-H5] (human) (rec.) (His)

Reference: AG-40B-0177

€0.00 (tax incl.)

Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with...

HpARI (Alarmin Release Inhibitor) (rec.) (His)

Reference: AG-40B-0178

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HpARI is a protein secreted by the mouse parasite Heligmosomoides polygyrus. The mature protein HpARI, containing three predicted Complement Control Protein (CCP)-like modules (also known as Short Consensus Repeats...

Nampt (mouse) (rec.) (enzymatically active)

Reference: AG-40B-0179

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Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD+) salvage...

Tim-4 (mouse):Fc (human) (rec.) (Biotin)

Reference: AG-40B-0180B

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Extracellular vesicles (EVs) are released by a variety of cells into the cellular microenvironment and have the natural ability of delivering different cargos and carry bioactive molecules such as non-coding RNA,...

VISTA (mouse):COMP (mouse) (rec.) (His)

Reference: AG-40B-0181

€0.00 (tax incl.)

Mouse VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with...

Lipoyl-TRIM21 (human) (rec.) (His)

Reference: AG-40B-0182

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TRIM21 (tripartite motif-containing protein 21) is a cytosolic Fc receptor induced by interferon (IFN). TRIM21 is distinguished from other Fc receptors by showing broad antibody specificity as it can activate its...

VISTA (human):COMP (mouse) (rec.) (His)

Reference: AG-40B-0183

€0.00 (tax incl.)

Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with...

Fc (human):FGL1 (human) (rec.)

Reference: AG-40B-0184

€0.00 (tax incl.)

FGL1 (Fibrinogen-like protein 1; also called Hepatocyte-derived fibrinogen-related protein 1; HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript...

Fc (human):FGL1 (mouse) (rec.)

Reference: AG-40B-0185

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FGL1 (Fibrinogen-like protein 1; also called Hepatocyte-derived fibrinogen-related protein 1; HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript...

FGL1 (human) (rec.) (His)

Reference: AG-40B-0186

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FGL1 (Fibrinogen-like protein 1, also called Hepatocyte-derived fibrinogen-related protein 1, HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript...

FABP3 (human) (rec.) (untagged)

Reference: AG-40B-6002

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FABP3 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs...

KillerTRAIL™, Soluble (human) (rec.)

Reference: AG-40T-0001

€0.00 (tax incl.)

TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved...

SuperKillerTRAIL™, Soluble (human) (rec.)

Reference: AG-40T-0002

€0.00 (tax incl.)

TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved...

SuperKillerTRAIL™, Soluble (mouse) (rec.)

Reference: AG-40T-0004

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TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved...

PARP-1 [ARTD1] (human) (rec.) (His) (high purity)

Reference: AG-40T-0011

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PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This...

PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)

Reference: AG-40T-0012

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PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This...

PARP-3 [ARTD3] (human) (rec.) (His) (high purity)

Reference: AG-40T-0013

€0.00 (tax incl.)

PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This...

PARP-1 [ARTD1] (E998K Mutant) (human) (rec.) Control

Reference: AG-40T-0015

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PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This...

CREB-binding Protein (mouse) (rec.) (His) (highly active)

Reference: AG-40T-0016

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CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances...

GCN5 (human) (rec.) (His) (highly active)

Reference: AG-40T-0017

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GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone...

TIP60 (human) (rec.) (His) (highly active)

Reference: AG-40T-0019

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TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This...

NF-kappaB (p65) (human) (rec.) (His) (highly active)

Reference: AG-40T-0020

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NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological...

NF-kappaB (p50) (human) (rec.) (His) (highly active)

Reference: AG-40T-0021

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NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological...

PARG (human) (rec.) (His) (highly active)

Reference: AG-40T-0022

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Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose...

FGF-2 (human) (rec.)

Reference: AG-40T-0040

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FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and...

EGFR, Soluble (human) (rec.)

Reference: AG-40T-0041

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EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding...

HGF (human) (rec.)

Reference: AG-40T-0042

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Human hepatocyte growth factor (HGF) is synthesized as a biologically inactive single chain precursor, which is cleaved by a specific, extracellular serum serine protease to a fully active heterodimer. It stimulates...

VEGF 165 (human) (rec.)

Reference: AG-40T-0043

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Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular...

VEGF 164 (mouse) (rec.)

Reference: AG-40T-0044

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Mouse vascular endothelial growth factor 164 (VEGF 164) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It is a specific mitogen for vascular endothelial...

VEGF 165 (human) (rec.)

Reference: AG-40T-0045

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Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular...

VEGF-C (human) (rec.) (His)

Reference: AG-40T-0046

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VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a...

PLGF (human) (rec.)

Reference: AG-40T-0047

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Human placenta growth factor-1 (PLGF-1; PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological...

VEGF-C (rat) (rec.) (His)

Reference: AG-40T-0048

€0.00 (tax incl.)

VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a...

VEGFR-1, Soluble (human) (rec.)

Reference: AG-40T-0049

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Recombinant human soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) is the naturally occurring form and is a glycosylated monomeric protein. The biological function of sVEGFR-1 seems to be an endogenous...

NAD Kinase (catalytic domain) (human) (rec.) (His) (highly active)

Reference: AG-40T-0090

€0.00 (tax incl.)

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism...

NAD Kinase (human) (rec.) (His) (highly active)

Reference: AG-40T-0091

€0.00 (tax incl.)

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism...

NMNAT1 (human) (rec.) (His) (highly active)

Reference: AG-40T-0092

€0.00 (tax incl.)

Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency....

NMNAT3 (human) (rec.) (His) (highly active)

Reference: AG-40T-0093

€0.00 (tax incl.)

Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same...

3-Hydroxykynurenine Transaminase (Anopheles gambiae) (rec.) (untagged)

Reference: AG-40T-0100

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The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of...

TDO (Anopheles gambiae) (rec.) (His)

Reference: AG-40T-0101

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Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles...

Kynurenine Aminotransferase II (human) (rec.) (His)

Reference: AG-40T-0102

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Kynurenine aminotransferases (KATs) are pyridoxal-5’-phosphate-dependent enzymes that catalyze the conversion of L-kynurenine into kynurenic acid, a neuroactive metabolite whose unbalancing is associated with a number...

Zmp1 (M. tuberculosis) (rec.) (His)

Reference: AG-40T-0103

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M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes...

NAPRTase (B. subtilis) (rec.)

Reference: AG-40T-0104

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Nicotinate Phosphoribosyltransferase (NAPRTase) is involved in the biological processes of pyridine nucleotide biosynthesis and nicotinate nucleotide salvage and functions by catalyzing the conversion of nicotinic...

NAPRTase (human) (rec.) (His)

Reference: AG-40T-0105

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Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate...

NAD Kinase (B. subtilis) (rec.)

Reference: AG-40T-0106

€0.00 (tax incl.)

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism...

NAD Kinase (M. tuberculosis) (rec.) (His)

Reference: AG-40T-0107

€0.00 (tax incl.)

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism...

NAD Synthetase (M. tuberculosis) (rec.) (His)

Reference: AG-40T-0108

€0.00 (tax incl.)

NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a...

NAD Synthetase (B. subtilis) (rec.)

Reference: AG-40T-0109

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NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a...

NAD Nucleotidase (H. influenzae) (rec.)

Reference: AG-40T-0110

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NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide...

Arginase I (human) (rec.) (highly active)

Reference: AG-40T-0124

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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic...

Streptavidin (R-PE)

Reference: ANC-253-050

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Streptavidin can be used in conjunction with biotinylated antibodies as an avidin/biotin labeling system for flow cytometry.

Streptavidin (FITC)

Reference: ANC-254-040

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Streptavidin can be used in conjunction with biotinylated antibodies as an avidin/biotin labeling system for flow cytometry.