Proteins & Peptides (268)

Recombinant human Ubiquitin-conjugating enzyme E2 R1/UBE2R1 protein

Reference: RP10055LQ

€0.00 (tax incl.)

Ube2R1 (UbcH3) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2R1 was first discovered during screening for cell cycle regulatory mutations that...

Recombinant human Ubiquitin-conjugating enzyme E2 T/UBE2T protein

Reference: RP10059LQ

€0.00 (tax incl.)

Ube2T is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2T interacts with the E3 ligase called Fanconi anemia complementation group L (FANCL) that...

Recombinant human Ubiquitin-conjugating enzyme E2 variant 2/UBE2V2 protein

Reference: RP10060LQ

€0.00 (tax incl.)

Ube2V2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2V2 is the human homolog of yeast Mms2 and shares 50% amino acid sequence identity. Its...

Recombinant human Ubiquitin-conjugating enzyme E2 W/UBE2W protein

Reference: RP10061LQ

€0.00 (tax incl.)

Ube2W is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to catalyze monoubiquitination of Fanconi anemia complementation group L...

Recombinant human Ubiquitin-conjugating enzyme E2 Z/UBE2Z protein

Reference: RP10062LQ

€0.00 (tax incl.)

Ube2Z is a member of the ubiquitin conjugating enzyme (E2) that specifically works with UBA6 (UBE1L2), but not UBE1, to transfer ubiquitin or the ubiquitin-like protein FAT10 to substrates. It is involved in...

Recombinant human Ubiquitin protein

Reference: RP10064LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (+1) protein

Reference: RP10065LQ

€0.00 (tax incl.)

Ubiquitin (+1) consists of the first 75 amino acids of ubiquitin, but lacks glycine 76 because of the deletion of two of the three nucleotides that encode glycine 76. The resulting frame shift leads to the addition of...

Recombinant human Ubiquitin (K all R) protein

Reference: RP10067LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K11 only) protein

Reference: RP10068LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K27 only) protein

Reference: RP10070LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K27R) protein

Reference: RP10071LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K29 only) protein

Reference: RP10072LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K29R) protein

Reference: RP10073LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K33 only) protein

Reference: RP10074LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K33R) protein

Reference: RP10075LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K6 only) protein

Reference: RP10078LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K63 only) protein

Reference: RP10079LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (K63R) protein

Reference: RP10080LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin (L73P) protein

Reference: RP10082LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(1-75) protein

Reference: RP10083LQ

€0.00 (tax incl.)

Ub75 lacks the amino acid glycine 76, which is required to form thioester bond with Ub activating enzyme E1. Therefore, Ub75 can not react with E1, E2 and E3 enzymes; and does not support ubiquitination. It can be...

Recombinant human Ubiquitin carboxyl-terminal hydrolase isozyme L5/UCH-L5 protein

Reference: RP10084LQ

€0.00 (tax incl.)

Uch37 is one of the deubiquitinating enzymes of the human 26S proteasome, belongs to the Ub C-terminal hydrolases. Uch37 was found to bind both Adrm1 and S5a subunits of the 26S proteasome. Uch37 likely contributes...

Recombinant human APPBP1&UBA3 protein

Reference: RP10088LQ

€0.00 (tax incl.)

APPBP1/UBA3 is the heterodimeric E1 enzyme that conjugates Nedd8 to protein substrates. Nedd8 is conjugated onto the catalytic cysteine residue of UBA3 by formation of a thioester bond in an ATP-dependent reaction....

Recombinant human OTU domain-containing protein 7B/Cezanne protein

Reference: RP10090LQ

€0.00 (tax incl.)

Cezanne (also called OTUD7B) is an ovarian tumor protein (OUT)-domain containing deubiquitinase that preferentially cleaves lysine 11-linked polyubiquitin, also exhibits activity for lysine 48 or lysine 63-linked...

Recombinant human Fluorescein labeled K63-Ub(2-7) protein

Reference: RP10094LQ

€0.00 (tax incl.)

This product contains authentic K63-linked isopeotide bonds, synthesized by an enzymatic reaction containing UbE1, GST-E2-25K and fluorescein-Ub (catalog # E1155/E1156). Mainly contain Ub(2-7) chains with residual...

Recombinant human TNF alpha-induced protein 3(1-365)/A20p50 protein

Reference: RP10098LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ataxin-3(Q22)/ATXN3 protein

Reference: RP10099LQ

€0.00 (tax incl.)

Ataxin3 is a Machado-Josephine domain-containing deubiquitinating enzyme. Machado–Joseph disease (MJD) is a neurodegenerative disorder caused by polyQ expansion in ataxin-3. Ataxin3 is involved in protein homeostasis...

Recombinant human HR23B/RAD23B protein

Reference: RP10101LQ

€0.00 (tax incl.)

hHR23A and hHR23B are the human homologues of yeast Rad23. Rad23 can interact with the Rpn10 and Rpn1 subunits of the 26S proteasome via its N-terminal Ub-like domain (UBL). Rad23 also contains two Ub-associated...

Recombinant human Josephin-2/JOSD2 protein

Reference: RP10102LQ

€0.00 (tax incl.)

JOSD2 (Josephin-2) is a member of the Machado-Joseph Domain (MJD) deubiquitinating enzyme family. Other family members include: Ataxin-3, Ataxin-3L, and JOSD1. JOSD2 preferentially cleaves K63-linked ubiquitin chains,...

Recombinant human linear Ub2 protein

Reference: RP10103LQ

€0.00 (tax incl.)

The linear ubiquitin chains are formed by conjugating the N-terminal methionine residue of one ubiquitin with the C-teminal glycine residue of another ubiquitin. This product is expressed in E. coli as a fusion protein.

Recombinant human linear Ub4 protein

Reference: RP10104LQ

€0.00 (tax incl.)

The linear ubiquitin chains are formed by conjugating the N-terminal methionine residue of one ubiquitin with the C-teminal glycine residue of another ubiquitin. This product is expressed in E. coli as a fusion protein.

Recombinant human E3 ubiquitin-protein ligase NEDD4 protein

Reference: RP10105LQ

€0.00 (tax incl.)

NEDD4 (neural precursor cell expressed developmentally down-regulated protein 4) is a widely expressed HECT domain-containing E3 ubiquitin ligase. NEDD4 ubiquitinates a few membrane proteins, including IGF-1R and...

Recombinant human NEMO/IKBKG protein

Reference: RP10106LQ

€0.00 (tax incl.)

NF-κB essential modulator (NEMO) is a regulatory subunit within IκB kinase (IKK). IKK is also composed of two unrelated catalytic subunits called IKKα and IKKβ. NEMO is additionally referred to as IKKγ, IKKAP1, or...

Recombinant human NEMO (UBAN)/IKBKG protein

Reference: RP10108LQ

€0.00 (tax incl.)

GST was fused on the N-terminus of the linear polyubiquitin chain binding domain of NEMO en-compassing amino acids 183-339. This fusion protein can be used for in vitro GST pulldown as-says and for enrichment of...

Recombinant human Ubiquitin thioesterase OTUB1 protein

Reference: RP10109LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human RING-finger 4/RNF4 protein

Reference: RP10111LQ

€0.00 (tax incl.)

RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding...

Recombinant human 26S proteasome non-ATPase regulatory subunit 4/S5A/PSMD4 protein

Reference: RP10112LQ

€0.00 (tax incl.)

S5a is one of the integral Ub receptors of the 26S proteasome. It’s N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs)...

Recombinant human SUMO-2 protein

Reference: RP10115LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human SUMO-3 protein

Reference: RP10117LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human TAK1-binding protein 2/TAB-2(627-693) (NZF) protein

Reference: RP10118LQ

€0.00 (tax incl.)

GST was fused on the N-terminus of the lysine 63 polyubiquitin chain binding domain of TAB2 encompassing amino acids 627-693. This fusion protein can be used for in vitro GST pulldown assays and for enrichment of...

Recombinant human TNF-alpha protein

Reference: RP10119LQ

€0.00 (tax incl.)

TNFalpha (Tumor necrosis factor alpha) is produced by immune and epithelial cells. It plays important roles in regulating inflammation, apoptosis, and immune response. It exerts its function mainly by binding of two...

Recombinant human Ubiquitin-conjugating enzyme E2 K/UBE2K protein

Reference: RP10120LQ

€0.00 (tax incl.)

Ube2K (or E2-25K) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It contains a C-terminal UBA domain and an E2 catalytic domain. Ube2K contains a...

Recombinant human Ubiquitin-protein ligase E3A/UBE3A protein

Reference: RP10121LQ

€0.00 (tax incl.)

UbE3A (also called E6AP) is a 100 kDa HECT (homologous to E6AP carboxyl terminus) domain ubiquitin ligase containing two E2 binding sites for UbcH7 and UbcH8. UbE3A was found to bind to the human papillomavirus (HPV)...

Recombinant human Ubiquitin protein

Reference: RP10122LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 21/USP21 protein

Reference: RP10129LQ

€0.00 (tax incl.)

USP21(195-565) contains the catalytic domain of USP21 and it is capable of cleavage of different types of polyubiquitin chains. USP21 can deubiquitinate histone H2A, a specific tag for epigenetic transcriptional...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 30(57-517)/USP30(57-517) protein

Reference: RP10130LQ

€0.00 (tax incl.)

USP30(57-517) contains the catalytic domain of USP30 with the N-terminal membrane bound domain being deleted. USP30 deubiquitinates substrates of Parkin including MIRO1, TOMM20, MFN1, and MFN2 on mitochondrial...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 4/USP4 protein

Reference: RP10131LQ

€0.00 (tax incl.)

Usp4 is a member of the ubiquitin-specific protease family of deubiquitinating enzyme. A number of substrates of Usp4 have been identified, including TRIM21, TRAF2, TRAF6, RIG-1, RIP1, PDK1, TAK1 and etc....

Recombinant human Sentrin-specific protease 2(catalytic domain)/SENP2 protein

Reference: RP10132LQ

€0.00 (tax incl.)

USP9X belongs to the ubiquitin-specific protease (USP) family. USP9X has been found to deubiqitinate more than a dozen of substrates including mcl1, survivin, SMAD4, SMN and Itch. USP9X is located on the X chromosome,...

Recombinant human ZnF-UBP/USP5 protein

Reference: RP10133LQ

€0.00 (tax incl.)

Usp5 (IsoT) is a deubiquitinase enzyme that hydrolyzes free polyubiquitin chains. The Usp5 contains two zinc finger domains (ZnF-UBP). This product contains the second ZnF-UBP domain (amino acid 163 – 291). The...

Recombinant human Ubiquitin protein

Reference: RP10134LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Heat shock 70 kDa protein 1A/HSP70 protein

Reference: RP10135LQ

€0.00 (tax incl.)

HSP70 a critical chaperone protein that has a high affinity for unfolded polypeptide chains. It binds extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane...

Recombinant human K11-Ub(n≥3) protein

Reference: RP10138LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K48-Ub(2-8) protein

Reference: RP10141LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K48-Ub2 protein

Reference: RP10142LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K48-Ub3 protein

Reference: RP10143LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K48-Ub4 protein

Reference: RP10144LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K63-Ub(2-12) protein

Reference: RP10146LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human K63-Ub2 protein

Reference: RP10147LQ

€0.00 (tax incl.)

Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link...

Recombinant human Linear Ub2 protein

Reference: RP10152LQ

€0.00 (tax incl.)

The linear ubiquitin chains are formed by conjugating the N-terminal methionine residue of one ubiquitin with the C-teminal glycine residue of another ubiquitin. This product is expressed in E. coli as a fusion protein.

Recombinant human Non-cleavable Linear Ub6 protein

Reference: RP10156LQ

€0.00 (tax incl.)

Non-cleavable linear Ub6 was a derivative of 6xHis-non-cleavable linear Ub6 by removal of the N-terminal 6xHis and 3xHA tags using TEV digestion. The G76V substitution was introduced in the first five Ub moieties and...

Recombinant human Non-cleavable SUMO-2 Chain (2-6) protein

Reference: RP10157LQ

€0.00 (tax incl.)

Non-cleavable SUMO2 chains are made of the SUMO2(Q90P) mutant, this substitution makes the formed polySUMO chains to be resistant to SENP proteases.

Recombinant human Ubiquitin thioesterase OTUB1 protein

Reference: RP10158LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin thioesterase OTUB2 protein

Reference: RP10159LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin thioesterase OTU1 protein

Reference: RP10160LQ

€0.00 (tax incl.)

OTUD2 belongs to the OTU (ovarian tumour) family of deubiquitinating enzymes. OTUD2 cleaves K-11, 27, 29 0r 33-linked polyubiquitin chains. It could be involved in regulating endoplasmic reticulum-associated...

Recombinant human Deubiquitinase OTUD6B protein

Reference: RP10161LQ

€0.00 (tax incl.)

OTUD6B belongs to the OTU (ovarian tumour) family of deubiquitinating enzymes. Functions of this enzyme are not clear. In vitro, purified OTUD6B has not activity for cleavage of various di-Ub chains.

Recombinant human Polyubiquitinated UbE2S protein

Reference: RP10164LQ

€0.00 (tax incl.)

Polyubiquitinated UbE2S (Ubn (K11-linked)-UbE2S) is a polyubiquitinated substrate in which various K11-linked polyUb chains were conjugated on the Ub conjugating enzyme UbE2S. It can be used as a substrate to monitor...

Recombinant human 26S proteasome non-ATPase regulatory subunit 4/S5A/PSMD4 protein

Reference: RP10165LQ

€0.00 (tax incl.)

S5a is one of the integral Ub receptors of the 26S proteasome. It’s N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs)...

Recombinant human SUMO-2 (Q90P) protein

Reference: RP10168LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human SUMO-3 protein

Reference: RP10170LQ

€0.00 (tax incl.)

SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like...

Recombinant human Ubiquitin(K0) protein

Reference: RP10176LQ

€0.00 (tax incl.)

All lysine residues in Ub(K0) were substituted with arginine residues, thereby Ub(K0) can only support monoubiquitination, but not polyubiquitination.

Recombinant human Ubiquitin(K11R) protein

Reference: RP10177LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K27R) protein

Reference: RP10178LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K29R) protein

Reference: RP10179LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(K63R) protein

Reference: RP10182LQ

€0.00 (tax incl.)

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be...

Recombinant human Ubiquitin(S20C) protein

Reference: RP10185LQ

€0.00 (tax incl.)

Ubiquitin (S20C) bears a single amino acid substitution that replaces serine 20 with a cysteine. This substitution has no effect on Ub’s structure and allows label Ub with other groups, such as biotin or fluorescent...

Recombinant human Ubiquitin(1-75) protein

Reference: RP10186LQ

€0.00 (tax incl.)

Ub75 lacks the amino acid glycine 76, which is required to form thioester bond with Ub activating enzyme E1. Therefore, Ub75 can not react with E1, E2 and E3 enzymes; and does not support ubiquitination. It can be...

Recombinant human Ubiquitin thioesterase L1/UCHL1 protein

Reference: RP10187LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin thioesterase L3/UCHL3 protein

Reference: RP10188LQ

€0.00 (tax incl.)

Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has...

26S proteasome

Reference: RP10189TLQ

€0.00 (tax incl.)

The 26S proteasome is an approximately 2.5 mDa large complex composed of the 20S proteasome and the 19S regulatory particle (also called PA700 in mammals). The 20S proteasome has 28 subunits that form a barrel –...

19S proteasome/PA700

Reference: RP10190TLQ

€0.00 (tax incl.)

The 19S regulatory particle (PA700) locates on either one or both ends of the 20S core particle of the 26S proteasome. It has 19 subunits including six AAA ATPases that associate with α subunits of the 20S proteasome...

immuno 20S proteasome

Reference: RP10192TLQ

€0.00 (tax incl.)

Upon stimulation with IFN – γ, the expression of the three catalytic β subunits β1, β2, and β5 with iso-forms β1i (LMP2), β2i (MECL – 1), and β5i (LMP7) are induced, respectively. These subunits are incorporated into...

Recombinant human Ubiquitin-activating enzyme E1/UBE1/UBA1 protein

Reference: RP10193LQ

€0.00 (tax incl.)

UBE1 is an E1 enzyme within the E1, E2, E3 cascade which conjugates Ub to protein substrates. UBE1 activates Ub by catalyzing an ATP – dependent reaction; Ub is conjugated onto the catalytic cysteine residue of UBE1...

K29-linked diUb

Reference: RP10197D

€0.00 (tax incl.)

This product is a native K29-linked diUb which can be used as a substrate of deubiquitinating enzyems. It can also be used to investigate linkage specificity of proteins that contain ubiquitin-associated domains or...

K33-linked diUb

Reference: RP10198D

€0.00 (tax incl.)

This product is a native K33-linked diUb which can be used as a substrate for deubiquitinating enzymes. It can also be used to investigate linkage specificity of proteins that contain ubiquitin-associated domains or...

N-terminal TAMRA-Ubiquitin

Reference: RP10200DLQ

€0.00 (tax incl.)

N-terminal TARMA-Ub (also called TARMA-Ub) is a fluorescent Ub, in which TAMRA (5-tetramethylrhodamine) is covalently conjugated on the N-terminus of Ub. All seven lysine residues in TARMA-Ub are available for...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 7/USP7 protein

Reference: RP10202LQ

€0.00 (tax incl.)

USP7 is a cysteine protease, belongs to the family of ubiquitin-specific proteases. USP7 was first discovered as a binding enzyme to the Herpes simplex viral protein. Studies have shown that USP7 could deubiquitinate...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 11/USP11 protein

Reference: RP10203LQ

€0.00 (tax incl.)

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 16 protein

Reference: RP10204LQ

€0.00 (tax incl.)

USP16 is an active deubiquitinating enzyme (DUB) encoded on chromosome 21, trisomy of which causes Down’s syndrome (DS). USP16 is a phosphoprotein, phosphorylation of USP16 controls its cellular localization, but no...

Recombinant human Ubiquitin carboxyl-terminal hydrolase 35/USP35 protein

Reference: RP10205LQ

€0.00 (tax incl.)

USP35 is a 1018 amino acid cysteine DUB that was found to be overexpressed in certain breast cancers. Its USP domain ranges from amino acids 425 to 926, with cysteine 450 as the catalytic cysteine residue.

E2 Screening Kit

Reference: RP10206K

€0.00 (tax incl.)

The E2 Screening Kit is developed for identification of the E2 Ub-conjugating enzyme(s) for a specific E3 Ub ligase and/or a protein substrate. This kit contains 29 E2 enzymes.

Di-ubiquitin Explorer Kit

Reference: RP10208K

€0.00 (tax incl.)

This kit contains 5 μg each of linear, K6, K11, K27, K29, K33, K48, and K63-linked diubiquitin, a total of eight different diubiquitin forms. It can be used for determining linkage specificity of deubiquitinating...

K48 polyUb Chain-binding Protein Identification / Validation Kit

Reference: RP10209K

€0.00 (tax incl.)

This kit is designed for two purposes: 1) identification of proteins that specially bind K48 polyUb chains in whole cell or tissue lysates; 2) validation of direct interactions between K48 polyUb chains and their...

K63 polyUb Chain-binding Protein Identification / Validation Kit

Reference: RP10210K

€0.00 (tax incl.)

This kit is designed for two purposes: 1) identification of proteins that specially bind K63 polyUb chains in whole cell or tissue lysates; 2) validation of direct interactions between K63 polyUb chains and their...

Sumo2 Conjugation Kit

Reference: RP10213K

€0.00 (tax incl.)

Sumo2 Conjugation Kit is designed for assaying the conjugation of Sumo2 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo activating enzyme SAE1/SAE2 (E1)...

Sumo3 Conjugation Kit

Reference: RP10214K

€0.00 (tax incl.)

Sumo3 Conjugation Kit is designed for assaying the conjugation of Sumo3 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo activating enzyme SAE1/SAE2 (E1)...

Sumo1, Sumo2, Sumo 3 Conjugation Kit

Reference: RP10215K

€0.00 (tax incl.)

Sumo1, Sumo2, Sumo 3 Conjugation Kit is designed for assaying the conjugation of Sumo1, Sumo2 and Sumo3 to protein substrates in vitro. In a protein sumoylation reaction, a Sumo protein is first activated by the Sumo...

Ubiquitin Linkage Screening Kit II

Reference: RP10218K

€0.00 (tax incl.)

Ubiquitin Linkage Screening Kit II is designed for two purposes: 1) to identify the ubiquitin lysine residue that is used to link the polyubiquitin chain conjugated on a protein substrate; 2) to determine whether a...

Proteasome Activity Fluorometric Assay Kit I

Reference: RP10220K

€0.00 (tax incl.)

Proteasome Activity Fluorometric Assay Kit I is designed for assaying the proteasome’s chymotrypsin-like activity in vitro using purified proteasome, cleared cell lysates or tissue extracts. The proteasome cleaves...

Proteasome Activity Fluorometric Assay Kit II

Reference: RP10221K

€0.00 (tax incl.)

Proteasome Activity Fluorometric Assay Kit II is designed for assaying the proteasome’s chymotrypsin-like, trypsin-like and caspase-like activities in vitro using purified proteasome, cleared cell lysates or tissue...

Immunoproteasome Activity Fluorometirc Assay Kit I

Reference: RP10222K

€0.00 (tax incl.)

Immunoproteasome Activity Fluorometric Assay Kit I was designed for assaying the immunoproteasomes'' chymotrypsin-like activity in vitro using purified proteasome, cell lysates or tissue extracts. The proteasome...

Rapid 26S Proteasome Purification Kit-L

Reference: RP10225K

€0.00 (tax incl.)

The Rapid 26S Proteasome Purification Kit is designed to rapidly purify the endogenous 26S proteasome from cell or tissue extracts within 8 hours according to a published method (reference 1) with modifications. This...

Category: Proteins & Peptides

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