Serum Retinol Binding Protein 4 (human recombinant) Reference: 10007818-100 Source: recombinant His-tagged protein purified from E. coli · Mr: ~21 kDa
Prostaglandin F Synthase (human, recombinant) Reference: 10007940-100 Source: Active recombinant C-terminal His-tagged protein expressed in E. coli · Mr: ~37 kDa · Protein concentration: 0.8 mg/ml • Human PGFS catalyzes the isomerization of PGH2 to PGF2a (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11b-PGF2a from PGD2 (PGD2 11-ketoreductase activity) in the presence of NADPH. This enzyme also exhibits reductase activities toward carbonyl compounds such at nitroacetophenone, nitrobenzaldehyde, and 9,10-phenanthrene quinine (PQ).
15-hydroxy Prostaglandin Dehydrogenase (human, recombinant) Reference: 10007950-100 Source: Active human recombinant N-terminal GST-tagged protein expressed in E. coli • MW: 55 kDa • NAD+-dependent 15-PGDH catalyzes the oxidation of PGs to 15-keto metabolites that have greatly reduced biological activity. Three different studies have shown an inverse correlation between 15-PGDH expression and cell proliferation in colon, breast, and thyroid cells.
PPARα Ligand-binding Domain (human, recombinant) Reference: 10009088-100 Source: Recombinant human His-tagged PPARα ligand-binding domain expressed in E. coli • Amino acids: 170-430 (full length) • MW: ~34 kDa/subunit
PCAF Histone Acetyltransferase Reference: 10009115-100 Source: Active recombinant GST-tagged protein expressed in E. coli · MW: ~40 kDa. PCAF belongs to the GCN5/PCAF family of nuclear HATs. Cayman’s PCAF preparation contains 165 amino acids from the HAT activity domain of human PCAF fused to GST at the N-terminus. Enzyme activity was determined using a fluorescent HAT assay and is comparable to that found in the literature.
HDAC1 (human, recombinant) Reference: 10009231-1 Source: 50 µg of full length recombinant C-terminal His- and FLAG-tagged protein expressed in baculovirus expression system • MW: 57 kDa • HDAC1 is a Class I HDAC that catalyzes the deacetylation of core histones and other non-histone proteins to control complex biological events, including cell development, differentiation, programmed cell death, angiogenesis, and inflammation.
HDAC3/NCOR2 (human, recombinant) Reference: 10009232-1 Source: 50 µg of a complex of full-length recombinant C-terminal His-tagged HDAC3 and recombinant N-terminal GST-tagged NCOR2 amino acids 395-489, co-expressed in baculovirus expression system · Mr: 49.7 kDa (HDAC3); 37.6 kDa (NCOR2) • HDAC3 is a Class I HDAC that is inactive alone and requires binding with the deacetylase activation domain of NcoR2 for activation.
HDAC2 (human, recombinant) Reference: 10009377-1 Source: 50 µg of full-length recombinant C-terminal His-tagged HDAC2 expressed in baculovirus expression system • Full length • MW: 56 kDa
HDAC5 (human, recombinant) Reference: 10009379-1 Source: 10 µg of recombinant C-terminal His-tagged protein expressed in baculovirus expression system · Mr: 51 kDa • HDAC5 is a Class IIa HDAC that can shuttle between the nucleus and cytoplasm, suggesting potential extranuclear functions by regulating the acetylation status of non-histone substrates.
HDAC6 (human, recombinant) Reference: 10009465-1 Source: 50 µg of full-length recombinant N-terminal GST-tagged protein expressed in baculovirus expression system · Mr: 159 kDa • HDAC6 is a Class II HDAC that can shuttle between the nucleus and cytoplasm, suggesting potential extranuclear functions by regulating the acetylation status of non-histone substrates.
HDAC9 (human, recombinant) Reference: 10009466-1 Source: 5 µg of recombinant C-terminal His-tagged protein expressed in baculovirus expression system · MW: 50.7 kDa • HDAC9 is a Class IIa HDAC that can shuttle between the nucleus and cytoplasm, suggesting possible extranuclear functions including regulating the acetylation status of non-histone substrates.
FABP1 (human, recombinant) Reference: 10009547-100 Source: Recombinant N-terminal hexahistidine-tagged protein expressed in E. coli • Mr: 18.3 kDa