Proteins & Peptides (2)

Melanotan (MT)-II

Reference: HY-P0267

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Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

Fmoc-Lys(Tfa)-OH

Reference: HY-W010830

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Fmoc-Lys(Tfa)-OH is a lysine derivative.

Colibactin

Reference: HY-145930

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Colibactin is a complex secondary metabolite produced by some genotoxic gut Escherichia coli strains. Colibactin has the potential for the research of colorectal cancer[1].

C-telopeptide

Reference: HY-P0284

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C-telopeptide, a cross-linked peptide of type I collagen, is released during bone resorption and has been correlated with bone mineral density (BMD).

SKF107457

Reference: HY-120880

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SKF107457 is an HIV-1 protease inhibitor that can be used in AIDS research.

M617 TFA is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617 TFA, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4...

Fmoc-D-Glu(OtBu)-OH

Reference: HY-Y1844

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Fmoc-D-Glu(OtBu)-OH is a glutamic acid derivative.

Mast cell degranulating peptide (28-49)

Reference: HY-P1987

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Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices.

H-Asp(Obzl)-OtBu.HCl

Reference: HY-W041996

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H-Asp(Obzl)-OtBu.HCl is an aspartic acid derivative.

Xenopsin-Related Peptide 2

Reference: HY-P3837

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Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as...

H-Asp(Oet)-OEt.HCl

Reference: HY-W008787

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H-Asp(Oet)-OEt.HCl is an aspartic acid derivative.

[Sar1, Ile8]-Angiotensin II

Reference: HY-P1564

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[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

Casein Kinase II Receptor Peptide

Reference: HY-P3748

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Casein Kinase II Receptor Peptide is a substrate for casein kinase II with an Km value of 500 µM. Casein Kinase II Substrate can be used for measure casein kinase II activity in crude enzyme preparations.

Insulin peglispro

Reference: HY-P4062

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Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins.

L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-D-leucyl]-, phenylmethyl ester

Reference: HY-79909

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L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-D-leucyl]-, phenylmethyl ester is a phenylalanine derivative.

β-Amyloid (1-43)(human) TFA

Reference: HY-P1378A

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β-Amyloid (1-43)(human) TFA is more prone to aggregation and has higher toxic properties than the long-known Aβ1-42. β-Amyloid (1-43)(human) TFA shows a correlation with both sAPPα and sAPPβ. β-Amyloid (1-43)(human)...

Tyroserleutide hydrochloride

Reference: HY-106263B

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Tyroserleutide hydrochloride, isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.

Compstatin control peptide

Reference: HY-P1398

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Compstatin control peptide is a negative control of Compstatin (HY-P1036). Compstatin is a potent complement system C3 inhibitor.

Sincalide

Reference: HY-P0093

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Sincalide (Cholecystokinin octapeptide, CCK‐8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. CCK‐8 is a major bioactive...

CMD178 TFA

Reference: HY-P1453A

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CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.

Fetuin, Fetal Bovine Serum

Reference: HY-P2352

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Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and...

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-carbamimidoyl-L-lysine

Reference: HY-W089229

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N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-carbamimidoyl-L-lysine is an arginine derivative.

SPACE peptide

Reference: HY-P0123

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SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid.

Renin substrate 1

Reference: HY-P3878

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Renin substrate 1 is a renin substrate with high affinity to the enzyme.

2-Furoyl-LIGRLO-amide

Reference: HY-P1314

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2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..

Boc-Gly-Gly-Phe-Gly-OH

Reference: HY-P1449

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Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

CALP2 TFA

Reference: HY-P1076A

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CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular...

Boc-D-3-Pal-OH

Reference: HY-W013874

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Boc-D-3-Pal-OH is an alanine derivative.

Secretin (swine)

Reference: HY-109538

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Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which...

[Ala3,11,18, Nle7] Endothelin-1, human

Reference: HY-P3614

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[Ala3,11,18, Nle7] Endothelin-1, human is a synthetic peptide.

Anti-BetaGamma

Reference: HY-P4074

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Anti-BetaGamma, a peptide, is MPS-Phosducin-like protein C terminus.

3-Aminooxolan-2-one hydrobromide

Reference: HY-W021299

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3-Aminooxolan-2-one hydrobromide is a serine derivative.

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm

Reference: HY-P1810

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c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is a is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.25 and 0.05 nM for hV2R and rV2R, respectively.

DL-Aspartic acid potassium salt

Reference: HY-W142113

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DL-Aspartic acid potassium salt is an aspartic acid derivative.

Diphenylmethylene-glycine benzyl ester

Reference: HY-W018620

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Diphenylmethylene-glycine benzyl ester is a Glycine (HY-Y0966) derivative.

CEF7, Influenza Virus NP (380-388)

Reference: HY-P1857

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CEF7, Influenza Virus NP (380-388) is a HLA-B*08 restricted influenza virus nucleoprotein epitope. Influenza virus NP functions as a key adapter molecule between virus and host cell processes.

Iseganan

Reference: HY-P3512

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Iseganan is an antimicrobial peptide, shows broad-spectrum anti-bacteria and fungi activity. Iseganan can be used in oral mucositis research.

N-[(Phenylmethoxy)carbonyl]-L-leucine

Reference: HY-Y0555

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N-[(Phenylmethoxy)carbonyl]-L-leucine is a leucine derivative.

D-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-, phenylmethyl ester

Reference: HY-79930

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D-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-, phenylmethyl ester is a phenylalanine derivative.

CTAP

Reference: HY-P1335

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CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP can be...

L-JNKI-1

Reference: HY-P0069A

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L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK.

Enterostatin(human,mouse,rat)

Reference: HY-P1067

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Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.

Peptide YY (PYY) (3-36), porcine TFA

Reference: HY-P1021A

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Peptide YY (PYY) (3-36), porcine TFA is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

Big Endothelin-2 (1-38), human

Reference: HY-P3734

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Big Endothelin-2 (1-38), human is a polypeptide.

BIO-11006 acetate

Reference: HY-106377A

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BIO-11006 acetate, an analog of the MANS peptide, is a MARCKS (myristoylated alanine-rich C kinase substrate) inhibitor.

β-Amyloid (22-35)

Reference: HY-P1474

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β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates...

Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride

Reference: HY-W009117

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Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride is a cysteine derivative.

NoxA1ds TFA

Reference: HY-P1435A

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NoxA1ds TFA is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds TFA exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. NoxA1ds TFA inhibits NOX1-derived O2-...

sGnRH-A acetate

Reference: HY-P3582A

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sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination.

Ezatiostat

Reference: HY-13634A

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Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting...

PL-017 TFA

Reference: HY-P1338A

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PL-017 TFA is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 TFA produces long-lasting, reversible analgesia in rats.

((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine

Reference: HY-W030573

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((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine is a phenylalanine derivative.

Z-Val-Ala-OH

Reference: HY-42709

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Z-Val-Ala-OH is a dipeptide derivative of valine and alanine.

WL12

Reference: HY-P3440

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WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression.

N-(4-Nitrobenzoyl)glycine

Reference: HY-W028991

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N-(4-Nitrobenzoyl)glycine is a Glycine (HY-Y0966) derivative.

Biotin-NeurokininA

Reference: HY-P3861

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Biotin-NeurokininA is a biotinylated NeurokininA (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human...

N-((Benzyloxy)carbonyl)-N-methyl-L-valine

Reference: HY-W011722

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N-((Benzyloxy)carbonyl)-N-methyl-L-valine is a valine derivative.

Acetyl Gastric Inhibitory Peptide (human)

Reference: HY-P3580

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Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory...

VKGILS-NH2

Reference: HY-P1310

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VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells.

Prolactin Releasing Peptide (12-31), human

Reference: HY-P1530

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Prolactin Releasing Peptide (12-31), human is a fragment of the prolactin releasing peptide (PrRP). Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin.

PKG inhibitor peptide TFA

Reference: HY-P1292A

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PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM.

RERHNGWRKSVLMVSYGFYVP

Reference: HY-P3464

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RERHNGWRKSVLMVSYGFYVP is a synthetic peptide.

α-Conotoxin PIA TFA

Reference: HY-P1268A

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α-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and...

H-His(1-Me)-OMe

Reference: HY-W016330

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H-His(1-Me)-OMe is a histidine derivative that can be used for amino acid synthesis.

Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate

Reference: HY-20153

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Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate is a Glycine (HY-Y0966) derivative.

OVA Peptide(257-264) TFA

Reference: HY-P1489A

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OVA Peptide(257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.

Endothelin 1 (swine, human), Alexa Fluor 488-labeled

Reference: HY-P2496

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Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin...

Neuromedin S(rat)

Reference: HY-P1239

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Neuromedin S(rat) is a 34-amino acids peptide from rat Neuromedin S. Neuromedin S is a neuropeptide isolated from rat brain. Neuromedin S acts as a ligand for the G protein-coupled receptor FM4/TGR-1

4-Fluoro-DL-glutamic acid

Reference: HY-W141942

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4-Fluoro-DL-glutamic acid is a glutamic acid derivative.

Ala-Gly-Ala

Reference: HY-P4242

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Ala-Gly-Ala is a prototype of a general tripeptide Xxx-Gly-Zzz. Except glycine and proline, there can be 18 possible amino acids for Xxx and another 18 amino acids for Zzz. Ala-Gly-Ala can be used as a model for up to...

Jagged-1 (188-204)

Reference: HY-P1846

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Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of...

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid hydrate

Reference: HY-W008667

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid hydrate is a glutamic acid derivative.

H-ILE-ARG-VAL-VAL-MET-OH

Reference: HY-P3972

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H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor.

GHGVYGHGVYGHGPYGHGPYGHGLYW

Reference: HY-P3401

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GHGVYGHGVYGHGPYGHGPYGHGLYW (DgHBP-2) is 26-amino-acid-long consensus peptide derived from histidine-rich beak protein-2 (DgHBP-2). GHGVYGHGVYGHGPYGHGPYGHGLYW can be used fabricated glucose-responsive insulin delivery...

Z-D-Phg-OH

Reference: HY-75332

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Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively.

GIP (3-42), human

Reference: HY-P2542

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GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo.

Substance P(1-4)

Reference: HY-P3598

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Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.

NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ

Reference: HY-P3142

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NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ is an angiotensin-converting enzyme 2 (ACE2) related peptide that can be used as a tool for understanding ACE2 functions.

Fequesetide

Reference: HY-P2463

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Fequesetide, a peptide segment, is the active site within the protein thymosin β4 responsible for actin binding, cell migration and wound healing.

Adipokinetic hormone (Gryllus bimaculatus)

Reference: HY-P3568

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Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus...

(S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid

Reference: HY-W007573

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(S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid is an aspartic acid derivative.

Boc-Gly-Gly-OH

Reference: HY-W013968

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Boc-Gly-Gly-OH is a Glycine (HY-Y0966) derivative.

Exendin (5-39)

Reference: HY-P2497

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Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats.

(Nle4)-α-MSH

Reference: HY-P3645

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(Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment.

Arg-Gly-Asp-Ser

Reference: HY-12290

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Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind...

Cyclo(Arg-Gly-Asp-D-Phe-Val)

Reference: HY-P1613

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Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia.

Mibenratide

Reference: HY-P3557

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Mibenratide, a small cyclic peptide, is an adrenergic β1 receptor antagonist. Mibenratide can be used for heart failure research.

Neuropeptide EI, rat

Reference: HY-P1869

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Neuropeptide EI, rat displays functional melanin concentrating hormone (MCH)-antagonist and melanocyte-stimulating hormone (MSH) agonist activity in different behavioral paradigms.

Ac-D-Ala-OH

Reference: HY-W012713

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Ac-D-Ala-OH is an alanine derivative.

CAP 37 (20-44)

Reference: HY-P3911

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CAP 37 (20-44) is a peptide based on amino acid residues 20 through 44 of CAP37. CAP37, a Cationic antimicrobial protein of 37 kDa, is a multifunctional protein.

FSLLRY-NH2

Reference: HY-P1260

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FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor.

Teduglutide

Reference: HY-P1624

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Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel...

(Gly22)-Amyloid β-Protein (1-42)

Reference: HY-P3845

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(Gly22)-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease. Mutation of Glu22...

H-Gly-OBzl.TosOH

Reference: HY-W011200

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H-Gly-OBzl.TosOH is a Glycine (HY-Y0966) derivative.

trans-N-Methyl-4-methoxyproline

Reference: HY-W065053

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trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative.

FFAGLDD

Reference: HY-P2004

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FFAGLDD is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release.

Fmoc-Asp(OcHex)-OH

Reference: HY-W013659

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Fmoc-Asp(OcHex)-OH is an aspartic acid derivative.

α-Helical CRF(9-41) TFA

Reference: HY-P1294A

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α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) TFA is also a partial agonist of CRF1 receptor with an EC50 of 140 nM.