Quote Debromohymenialdisine
Protein kinase C (PKC) inhibitor. Inhibits the ATP binding site [1]. Cytotoxic and insecticidal [2]. G2 DNA damage checkpoint inhibitor. Check point kinases 1 (Chk1) and 2 (Chk2) inhibitor [3, 4, 6]. Does not inhibit ataxia-telangiectasia mutated (ATM) or ATM-Rad3-related proteins [3, 4]. MAP kinase kinase 1 (MEK-1) inhibitor [5]. Interleukin-1 (IL-1) inhibitor. Anti-osteoarthritic [7]. Potential anti-Alzheimer agent [7].
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Reference:
AG-CN2-0068
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