Quote (25S)-Delta7-Dafachronic acid
Ligand of DAF-12, an orphan nuclear receptor, that regulates dauer diapause, reproductive development, fat metabolism, and life span (life cycle) in parasitic nematodes [1, 2, 3]. Sterol-derived hormone. Blocks formation of infective larvae in several parasitic nematodes [4, 5]. Inhibits the dauer-promoting activity of DAF-12 [4, 5]. Supports the reproductive development [4, 5].
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Reference:
AG-CN2-0014
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