Human IL28B protein, His tag (active)

This gene encodes a cytokine distantly related to type I interferons and the IL-1 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 1 receptor, beta (IL1RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 28]