anti-GM-CSF antibody [429] (HRP)

GM-CSF is an extracellular homodimer polyprotein, functioning as a hematopoietic growth factor and immune modulator. It can be produced and act upon a variety of cell types, including T-lymphocytes, B-lymphocytes, monocytes/macrophages, endothelial cells, fibroblasts, stromal cells, mesothelial cells, keratinocytes, osteoblasts, uterine epithelial cells, synoviocytes, mast cells and various solid tumors. GM-CSF stimulates stem cells to produce granulocytes and monocytes to cope with infection. Recombinant GM-CSF has been applied to boost white blood cell in cancer patients after chemotherapy and may also be useful as an immune tonic for anemia and AIDS patients.