Category: Reagents

Reference: CDX-Y0346
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Acetonedicarboxylic acid is primarily used as building blocks in organic chemistry, particularly in the synthesis of heterocyclic rings and in the Weiss-Cook reaction.
Reference: SBB-PS0130
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KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving...
Reference: AG-CR1-3757
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Selumetinib is an orally available, potent and selective ATP non-competitive inhibitor of the mitogen-activated protein kinases MEK1 (IC50 = 14 nM) and MEK2 (Kd = 530 nM). MEK1 and MEK2 specifically act downstream of...
Reference: AG-CP3-0038
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Boc-Val-Pro-Arg-AMC is a sensitive fluorogenic peptide substrate for α-thrombin (Km = 21 μM, kcat = 109 s-1) and the α-thrombin-staphylocoagulase complex (Km = 25 μM, kcat = 89 s-1). It also serves as a substrate vor...
Reference: BVT-0480
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Collinolactone has neuroprotective and anti-neurodegenerative effects by reducing intracellular oxidative stress. It protects against glutamate-induced oxidative stress in a dose-dependent manner. Collinolactone is a...
Reference: AG-CN2-0440
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Antibiotic. Inhibits the growth of several Gram-positive and Gram-negative bacteria. Binds to MreB inducing disruption of the bacterial cell wall. Competitive inhibitor of muscarinic acetylcholine receptors (mAChR)....
Reference: AG-CN2-0542
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Daptomycin, a naturally occurring cyclic lipopeptide, is a calcium-dependent antibiotic. It exhibits potent bacteriocidal activity against most Gram-positive bacteria in vitro and in vivo, including...
Reference: AG-CR1-3545
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Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise in mammals and acts to reduce food intake and potentially decrease...
Reference: AG-CR1-3546
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Ipragliflozin is an orally active, highly potent sodium glucose co-transporter 2 (SGLT-2) inhibitor (IC50 = 7.4nM), selective over SGLT-1, 3, 4, 5 and 6. SGLT-2 is one subtype of SGLTs found almost exclusively in the...
Reference: AG-CR1-3547
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RBN-2397 is a potent NAD+ competitive small molecule inhibitor of PARP-7. RBN-2397 selectively inhibits PARP-7 and demonstrates >50-fold selectivity for inhibition of PARP-7 over all PARP family members as measured by...
Reference: CDX-A0247
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S-Adenosylmethionine (SAM) is the first product of the methionine cycle and is implicated in the synthesis of polyamines and in the transsulfuration pathway leading to homocysteine and reduced glutathione (GSH)...
Reference: CDX-A0286
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Amikacin is a broad-spectrum aminoglycoside antibiotic and a semisynthetic analog of kanamycin. It irreversibly binds to 16S rRNA and the RNA-binding S12 protein of the 30S subunit and 50S subunit of prokaryotic...
Reference: CDX-A0732
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Azelaic acid dichloride is a bulding block for synthesis (e.g. copolymers). It is the diacid chloride derivative of azelaic acid.
Reference: CDX-B0626
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11-Bromo-1-undecanol is a bulding block for synthesis. It was used in the preparation of graft copolymers based on a metathesis skeleton with poly(methyl methacrylate) grafts and in the synthesis of polymerizable tail...
Reference: CDX-C0357
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Coumarin-3-carboxylic acid can be used for quantitative, sensitive, specific detection of hydroxyl radicals (.OH) in aqueous solutions. Spectral Data: lambdaex=395nm; lambdaem=450nm. Fluorescence detection of 3-CCA...
Reference: CDX-C0727
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Cnidilin is a natural compound belonging to the coumarin family and normally isolated from Radix Angelicae dahuricae (RAD), a traditional Chinese medicine (TCM). RAD possesses anti-oxidant, anti-cancer and...
Reference: CDX-C0753
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Organosilicon compounds are organometallic compounds containing carbon-silicon bonds. Organosilicon compounds are widely encountered in commercial products. Most common are antifoamers, caulks (sealant), adhesives,...
Reference: CDX-C0779
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cis-1,4-Dichloro-2-butene is a bulding block and intermediate used in the synthesis and for the production of other chemicals such as acrylonitrile, adiponitrile, butane-1,4-diol, chloroprene and tetrahydrofuran. It...
Reference: CDX-E0582
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Methyl ethanesulfonate is a bulding block and intermediate used in the synthesis. Methyl ethanesulfonate belongs to the group of alkyl sulfonate esters, termed as potential genotoxic impurities (GTIs). Methyl...
Reference: CDX-H0150
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4-Hydroxytamoxifen is an active metabolite of the chemotherapeutic drug tamoxifen, a selective estrogen receptor modulator (SERM) that acts as an agonist or antagonist in various tissues. 4-Hydroxytamoxifen acts as a...
Reference: CDX-H0281
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L-Homoserine lactone is a synthetic building block or intermediate used in the synthesis of organoselenium chemistry intermediates and analogs of bacterial quorum-sensing signaling molecules.
Reference: CDX-H0379
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N-Z-L-Homoserine lactone is a synthetic building block or intermediate used in the synthesis of biological active agents and analogs of bacterial quorum-sensing signaling molecules. N-Z-L-Homoserine lactone is shown...
Reference: CDX-M0183
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Mevastatin is an antibiotic that is a competitive HMG-CoA reductase inhibitor, thus suppressing Ras farnesylation. Mevastatin decreases cholesterol biosynthesis in vitro and in vivo. It induces apoptosis, arrests...
Reference: CDX-M0698
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Methanesulfonic anhydride is a building block for organic synthesis. It is used to prepare methylsulfonyl esters, also called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with...
Reference: CDX-N0236
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N-Nonanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression and affecting cellular metabolism. The diverse applications of this kind of molecule...
Reference: CDX-N0270
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N-Nonanoyl-DL-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression and affecting cellular metabolism. The diverse applications of this kind of molecule...
Reference: CDX-N0360
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Nimbolide is a limonoid tetranortriterpenoid shown to exhibit anti-malarial, anti-bacterial, anti-inflammatory, anti-obesity and anti-cancer activities. Nimbolide induces cell cycle arrest, DNA damage and apoptosis,...
Reference: CDX-N0516
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IR-820 is a near infrared dye (NIR), which has a broad absorption band at 690nm in aqueous solution, with high resistance to photodegradation and photocleavage. IR-820 is an excellent probe for imaging tumors, as it...
Reference: CDX-O0187
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Oxydemeton-methyl is an organothiophosphate insecticide. Acetylcholinesterase (AChE) inhibitor in the nervous system. Primarily used to control aphids, mites, and thrips. Compound can be used as analytical reference...
Reference: CDX-T0114
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Thiamethoxam is a broad-spectrum, systemic neonicotinoid insecticide, which means it is absorbed quickly by plants and transported to all of its parts, including pollen, where it acts to deter insect feeding. The...
Reference: CDX-T0543
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ETH 500 is a lipophilic electrolyte mostly used as an anionic additive for membranes of neutral carrier-based ion-selective macroelectrodes or in membranes of optodes. ETH 500 is a reagents for electrochemistry and...
Reference: IAX-200-056
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In recent years several groups have studied the sequence requirements, specificity, signaling pathways and kinetics of the TLR (Toll-like receptor) 9 suppression by inhibitory oligonucleotide motifs, which led to a...
Reference: IAX-700-100
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A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition...
Reference: IAX-700-101
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Curcumin (high purity) Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Curcumin is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with...
Reference: IAX-700-102
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Melatonin (high purity) Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Melatonin, an evolutionarily ancient derivative of serotonin with hormonal properties, is the main neuroendocrine...
Reference: IAX-700-103
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Metformin Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Metformin is an antihyperglycemic agent of the biguanide class, used for the management of type II diabetes and is currently...
Reference: IAX-700-104
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Oxyresveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Oxyresveratrol is a naturally occurring analog of resveratrol. Potent antioxidant and free-radical scavenger. Shown to have...
Reference: IAX-700-105
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Resveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor....
Reference: IAX-700-106
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Umifenovir Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Umifenovir (Arbidol) is known to have broad-spectrum anti-viral activity and has earlier been approved in China and Russia for...
Reference: IAX-700-107
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Dexamethasone Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Dexamethasone, developed in 1957 and granted FDA approval in 1958, is a corticosteroid structurally similar to hydrocortisone...
Reference: IAX-700-108
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Ambroxol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Ambroxol is a mucolytic agent used in the treatment of respiratory diseases. Ambroxol is a basic (pKa = 9.01) cationic drug with...
Reference: AG-CN2-2000
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Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect...
Reference: AG-CP3-0043
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Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide potently activates the GLP-1R signaling pathway to stimulate...
Reference: AG-CR1-3548
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m-3M3FBS is a cell permeable and specific activator of phospholipase C (PLC) that has been shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production and superoxide generation in...
Reference: AG-CR1-3575V
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Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma...
Reference: AG-CR1-3549
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SP600125 is an orally active, reversible and ATP-competitive broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 (IC50 = 40nM, 40nM and 90nM, respectively). In Jurkat T cells, SP600125 suppressed the phosphorylation...
Reference: AG-CR1-3550
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CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2 and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCalpha,...
Reference: AG-CR1-3551
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WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines (such as IL-6 and IL-3) through...
Reference: AG-CR1-3552
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b-AP15 is a specific deubiquitinase (DUB) inhibitor. It inhibits ubiquitin-specific-processing protease 14 (USP14) and ubiquitin c-terminal hydrolase isozyme L5 (UCHL5; UCH37), two 19S regulatory particle...
Reference: CDX-A0029
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7-Amino-4-trifluoromethylcoumarin (AFC) is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids and therefore the precursor for a variety of AFC enzyme substrates....
Reference: CDX-A0052
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Ammonium 4-chloro-7-sulfobenzofurazan (SBF-Cl) is a water-soluble fluorogenic reagent which is highly specific for thiol groups. SBF-Cl is a very good substrate for the investigation of glutathione S-transferases...
Reference: CDX-A0313
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Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria. Formulations containing ampicillin have been used to treat a variety of bacterial infections. This is a...
Reference: CDX-A0712
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Acetamidofluorescein is a N-acetyl derivative of fluorescein that is strongly fluorescent und used as a fluorescent label. Spectral data: lambdaex = 491nm, lambdaem 515nm.
Reference: CDX-B0024
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BCIP is a colorimetric substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, an indoxyl intermediate is released and subsequently oxidized to produce water-insoluble indigo. It can be...
Reference: CDX-B0658
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Intermediate to produce the activated Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 ester, suitable for 1D- or 2D-protein gel staining and for acylation of amino acid side chain amines. Used to derivatize polymers and...
Reference: CDX-B0697
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Aripiprazole is an atypical antipsychotic. Aripiprazole is a partial agonist at dopamine D2 receptors, partial agonist at 5-HT1A receptors and an antagonist at 5-HT2A, receptors....
Reference: CDX-C0239
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Cucurbit[6]uril hydrate belongs to the Cucurbit[n]uril (CB[n], n = 5-10) family of macrocyclic compounds comprising n glycoluril units, self-assembled from an acid-catalyzed condensation reaction of glycoluril and...
Reference: CDX-D1217
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DAPI (4,6-Diamidino-2-phenylindole dihydrochloride) is a cell permeable, fluorescent dye that is a minor groove-binding probe for DNA. Binds to the minor groove of double-stranded DNA (preferentially to AT rich DNA),...
Reference: CDX-M0116
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7-Methylcoumarin is an inhibitor for CYP2A6. It has strong hepatoprotective activity, which could be attributed to its potent antioxidant effects. 7-Methylcoumarin has moderate antimicrobial activity. The compound can...
Reference: CDX-N0244
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Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-BI-phosphate is converted to naphthol AS-BI (N-ASBI) displaying excitation/emission spectra of 405/515nm. N-ASBI...
Reference: CDX-R0006
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Resorufin-beta-D-glucopyranosid is a non-selective red-fluorogenic substrate. It is a fluorogenic substrate for beta-glucosidase, beta-glucocerebrosidase (GCase) and beta-galactosidase. Upon enzymatic cleavage by the...
Reference: CDX-R0014
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Resorufin benzyl ether (7-Benzyloxyresorufin) is a fluorogenic substrate widely used for monitoring cytochrome P450 (CYP450) activities in cell extracts and solutions. It is the model substrate for...
Reference: CDX-R0015
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Resorufin pentyl ether (7-Pentoxyresorufin) is a fluorogenic substrate used for monitoring cytochrome P450 (CYP450) activities in cell extracts and solutions. It is used as substrate for...
Reference: CDX-R0020
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Resorufin acetate is a fluorogenic substrate for hydrolytic esterases and cellulases used for monitoring cytosolic aldehyde dehydrogenase (ALDH1A1) esterase activity, chymotrypsin activity. Resorufin acetate has been...
Reference: CDX-R0137
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Rhodamine 800 is a near-infrared fluorescent dye, which was originally developed as a laser dye. Rhodamine 800 belongs to the rhodamine family and is one of the few rhodamines that have near infrared fluorescence. It...
Reference: CDX-T0043
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TMA-DPH is a fluorescent probe for membrane fluidity measurements in artificial and living membrane systems. Acts as an anchor at the lipid/water interface. Specifically and rapidly incorporating into the plasma...
Reference: CDX-T0909
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1,8-Bis(dimethylamino)naphthalene (Proton Sponge) is an organic compound that has several very interesting properties. One is its very high basicity, another is its spectroscopic properties. It is a very strong base...
Reference: AG-CP3-0044
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Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human...
Reference: AG-CR1-3553
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AOH1996 is an orally available and metabolically stable small molecule PCNA inhibitor, which selectively kills cancer cells, with a median concentration of about 300 nM for 50% growth inhibition. AOH1996 was not...
Reference: CDX-C0752
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2-Chloro-1,3-propanediol (2-MCPD) is a heat-induced food contaminant present in oil- and fat-containing foodstuff. 2-MCPD is formed during the refinement of vegetable oils and fats and is therefore present in numerous...
Reference: CDX-D0559
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D-Sphingosine is a characteristic structural unit of many sphingolipids such as ceramides, gangliosides, globosides, sulfatides, sphingomyelin, and others. It is most abundant in nervous tissue and cell membranes....
Reference: CDX-D0619
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Deltamethrin belongs to the class of synthetic pyrethroids, which are being widely used as insecticides. Deltamethrin acts on voltage-gated sodium channels (VGSCs) and voltage-gated calcium channels (VGCCs) that are...
Reference: CDX-D0698
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Diquat dibromide is a non-selective contact herbicide that produces desiccation and defoliation. When acting as a herbicide, diquat inhibits photosynthesis (electron transport). In light-exposed plants, it accepts an...
Reference: CDX-D0810
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Chromoionophore VI (ETH 7075), a synthetic compound composed of a chromophore and an ionophore; is as an acidic lipophilic pH indicator and is generally used during the fabrication of optical sensors/membranes....
Reference: CDX-D1098
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Diquat metabolite dipyridone is a common degradation product of diquat. Diquat is a nonselective, defoliant, preharvest, and non-residual bipyridyl herbicide and crop desiccant, normally used as the dibromide salt, to...
Reference: CDX-H0455
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Hexamethonium bromide is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs). Formulations containing...
Reference: CDX-L0110
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L-Lysine is an essential alpha-amino acid, which is encoded by the codons AAA and AAG. It is a key building block in protein synthesis in which it acts as a base. Lysine residues are useful in many cellular processes,...
Reference: CDX-M0701
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2-Morpholinoethyl isocyanide is a buildig block and intermediate for organic synthesis. The principal synthetic application of 2-morpholinoethyl isocyanide is as a coupling reagent of amino acids to yield peptides. It...
Reference: CDX-M0730
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4-Methoxyphenyl isocyanide is a buildig block and intermediate for organic synthesis. This compound is colorless and volatile liquid when maintained at room temperature and it is extensively used in synthesis for many...
Reference: CDX-N0126
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Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-BI-phosphate is converted to naphthol AS-BI (N-ASBI) displaying excitation/emission spectra of 405/515nm. N-ASBI...
Reference: CDX-N0127
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Naphthol AS-MX Phosphate is a fluorogenic substrate for alkaline phosphatases. Naphthol AS-MX Phosphate is converted to naphthol AS-MX displaying excitation/emission spectra of 388/512nm. The fluorescence is a...
Reference: CDX-N0128
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Naphthol AS-TR Phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-TR Phosphate is converted to naphthol AS-TR displaying excitation/emission spectra of 388/512nm. The fluorescence is...
Reference: CDX-N0130
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Naphthol AS phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS phosphate is converted to naphthol AS displaying excitation/emission spectra of 388/516nm. The fluorescence is a...
Reference: CDX-N0239
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Naphthol AS-BI is a fluorescent dye commonly used as a building block or intermediate to produce fluorigenic substrates or as a coupling reagent to produce azo dyes. After cleavage of the fluorigenic substrates by...
Reference: CDX-N0240
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Naphthol AS phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS phosphate is converted to naphthol AS displaying excitation/emission spectra of 388/516nm. The fluorescence is a...
Reference: CDX-N0245
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Naphthol AS-D chloroacetate (NASDCA) is a fluorigenic substrate for granulocyte specific esterases (e.g. Proteinase 3 (PR3) and Cathepsin G). It can be hydrolyzed into Naphthol AS-D by esterases to mix with diazonium...
Reference: CDX-N0246
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Naphthol AS-MX Phosphate is a fluorogenic substrate for alkaline phosphatases. Naphthol AS-MX Phosphate is converted to naphthol AS-MX displaying excitation/emission spectra of 388/512nm. The fluorescence is a...
Reference: CDX-N0247
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Naphthol AS-TR Phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-TR Phosphate is converted to naphthol AS-TR displaying excitation/emission spectra of 388/512nm. The fluorescence is...
Reference: CDX-N0354
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Naphthol AS acetate is a fluorogenic substrate for unspecified esterases. After cleavage of the fluorigenic substrate by esterases the free Naphthol AS can couple with diazonium salts to form different types of...
Reference: CDX-N0529
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Naphthol AS (3-Hydroxy-2-naphthanilide) is a fluorescent dye commonly used as a building block or intermediate to produce fluorigenic substrates, bioactive chemicals or as a coupling reagent to produce azo dyes. After...
Reference: CDX-P0508
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(S)-Pulegone is a monoterpene utilized as a particularly actractive chiral starting material for the synthesis of more complex natural products. This compound has also shown to have antimalarial properties.
Reference: CDX-P0591
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Procyanidin B2, one of the most representative naturally occurring edible pigments, is usually isolated from the seeds, fruits and leaves of lots of common plants, such as grapes or apples. Procyanidin B2 has numerous...
Reference: CDX-P0933
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Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the...
Reference: CDX-Q0014
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Quinine hydrochloride dihydrate is isolated from the cinchona tree?s bark, is characterized by a bitter taste and shows antipyretic (fever-reducing), anti-malarial, analgesic (painkilling), anti-viral and...
Reference: CDX-Q0029
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Quinidine is a dextrorotatory stereoisomer of Quinine with anti-malarial, anti-arrhythmic (class 1A), anti-inflammatory, anti-cancer and anti-viral properties. Quinidine acts as a blocker of voltage-gated sodium...
Reference: CDX-R0005
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Resorufin beta-D-galactopyranoside is a fluorogenic substrate for beta-galactosidase. Upon enzymatic cleavage by the enzymes, the fluorescent hydrolysis product resorufin is released and its fluorescence can be used...
Reference: CDX-S0145
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Sodium salicylate is a metabolite of aspirin. It is a cell-permeable, non-steroidal anti-inflammatory agent (NSAID) that interferes with TNF-induced NF-kappaB activation by inhibiting phosphorylation and subsequent...
Reference: CDX-T0458
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2,4,6-Tris(2-pyridyl)-s-triazine (TPTZ) is commonly used as a complexing reagent used in spectrophotometric analysis, particularly in the determination of iron(II) (ferrous) ions in solution. It forms a blue-colored...

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